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About This Item
经验公式（希尔记法）:
C21H20O12
CAS号:
分子量:
464.38
Beilstein:
100989
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.25
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化驗
≥90% (HPLC)
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
−20°C
SMILES 字串
OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1
InChI 密鑰
OVSQVDMCBVZWGM-QSOFNFLRSA-N
基因資訊
mouse ... Hexa(15211)
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一般說明
槲皮素 3-β-D-葡糖苷（Q3G），也叫作异槲皮苷，是槲皮素的主要糖苷形式之一。它是一种单葡萄糖苷，最早从加拿大紫荆的种荚中分离出来，也广泛存在于各种植物、蔬菜和水果中。Q3G 具有类黄酮的基本化学结构，即一个葡萄糖分子连接在槲皮素的 C-3 上。
應用
使用槲皮素 3-β-D-葡糖苷：
- 作为膳食类黄酮补充剂，以利用表面等离子共振（SPR）检测其与人类小泛素相关修饰物 1（SUMO1）蛋白的结合能力
- 用为大肠杆菌三磷化酸腺苷（ATP）合成酶的抑制剂
- 作为抗聚集剂，测试其对β-淀粉样蛋白、绿色荧光蛋白（GFP）和胰凝乳蛋白酶原蛋白的活性
生化／生理作用
槲皮素 3-β-D-葡糖苷具有较强的抗氧化和抗炎活性。作为一种强效氧自由基清除剂，它是一种神经保护剂，可在小鼠模型中改善阿尔茨海默病（AD）的症状。′它可与苹果提取物结合使用，对结肠癌、肺癌和肝癌细胞系以及 MCF-7 人乳腺细胞具有抗增殖活性。
包裝
无底玻璃瓶。内含物在插入的融合锥体内。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Quercetin and quercetin-3-beta-d-glucoside improve cognitive and memory function in Alzheimer?s disease mouse
Kim J H, et al.,
Applied Biological Chemistry, 721-728 (2016)
Jun Yang et al.
Journal of agricultural and food chemistry, 57(18), 8581-8586 (2009-08-22)
Breast cancer is the most frequently diagnosed cancer in women. An alternative strategy to reduce the risk of cancer is through dietary modification. Although phytochemicals naturally occur as complex mixtures, little information is available regarding possible additive, synergistic, or antagonistic
Prasanna K Dadi et al.
International journal of biological macromolecules, 45(1), 72-79 (2009-04-21)
We have studied the inhibitory effect of five polyphenols namely, resveratrol, piceatannol, quercetin, quercetrin, and quercetin-3-beta-D glucoside on Escherichia coli ATP synthase. Recently published X-ray crystal structures of bovine mitochondrial ATP synthase inhibited by resveratrol, piceatannol, and quercetin, suggest that
Ali Reza A Ladiwala et al.
Biotechnology and bioengineering, 109(7), 1869-1874 (2012-02-15)
Protein aggregation is a common problem during the purification and formulation of therapeutic proteins. Here we report that polyphenolic disaccharides are unusually effective at preventing protein aggregation. We find that two polyphenolic glycosides-naringin and rutin-endow diverse proteins with the ability
Kateřina Valentová et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 267-282 (2014-04-01)
The flavonoid isoquercitrin (quercetin-3-O-β-d-glucopyranoside) is commonly found in medicinal herbs, fruits, vegetables and plant-derived foods and beverages. This article reviews the occurrence, preparation, bioavailability, pharmacokinetics, toxicology and biological activity of isoquercitrin and "enzymatically modified (α-glucosylated) isoquercitrin" (EMIQ). Pure isoquercitrin can
实验方案
HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)
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