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Merck

Y0001207

蛇床子素

European Pharmacopoeia (EP) Reference Standard

别名:

7-甲氧基-8-异戊烯基香豆素, 7-甲氧基-8-(3-甲基-2-丁烯基)香豆素, 蛇床子素

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About This Item

经验公式(希尔记法):
C15H16O3
CAS号:
分子量:
244.29
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

osthole

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C

InChI

1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

InChI 密鑰

MBRLOUHOWLUMFF-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Osthole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

传统中药 蛇床子的有效成分,具有抗炎、镇痛、降脂等作用。在鹌鹑模型中显著降低脂质蓄积。它对MPP(+)诱导的PC12细胞中细胞毒性的神经保护作用支持使用蛇床子素作为治疗神经退行性疾病的治疗剂。在 HER2 过度表达的乳腺癌细胞中抑制脂肪酸合成酶的表达表明蛇床子素有望成为化疗药物。

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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Osthole attenuates lipid accumulation, regulates the expression of inflammatory mediators, and increases antioxidants in FL83B cells.
Huang W C, et al.
Biomedicine and Pharmacotherapy, 91, 78-87 (2017)
Ola D Alabi et al.
Life sciences, 102(2), 105-110 (2014-03-25)
Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines

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