PHR3060

Anatabine

pharmaceutical secondary standard, certified reference material

• 别名: Anatabine, (RS)-Anatabine, (±)-Anatabine, 1,2,3,6-Tetrahydro-2,3′-bipyridine, 1,2,3,6-Tetrahydro-2,3′-dipyridine
• 经验公式（希尔记法）: C₁₀H₁₂N₂
• CAS号: 2743-90-0
• 分子量: 160.22
• 分類程式碼代碼: 12352210
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1463326
• API 家族: nicotine
• CofA: current certificate can be downloaded
• 包裝: pkg of 50 mg
• 應用: pharmaceutical
• 儲存溫度: 2-8°C
• InChI: 1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2
• InChI 密鑰: SOPPBXUYQGUQHE-UHFFFAOYSA-N

说明

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

Anatabine is a blood-brain barrier penetrant minor alkaloid, a cholinergic agonist, isolated from Solanaceae plant family that exhibits anti-inflammatory properties. Apparently, anti-inflammatory properties of anatabine are partially mediated by inhibition of STAT3 and p65 NFkB phosphorylation. Anatabine decreases the transcription and protein synthesis of β-secretase (BACE-1), and appears to ameliorate experimental autoimmune thyroiditis and encephalomyelitis.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H319
• 防範說明: P264 - P270 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable