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等級
pharmaceutical primary standard
API 家族
neostigmine
製造商／商標名
EDQM
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-8°C
SMILES 字串
[Br-].CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
InChI
1S/C12H19N2O2.BrH/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;/h6-9H,1-5H3;1H/q+1;/p-1
InChI 密鑰
LULNWZDBKTWDGK-UHFFFAOYSA-M
基因資訊
human ... ACHE(43)
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Neostigmine bromide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化／生理作用
类似于毒扁豆碱的乙酰胆碱酯酶的可逆抑制剂，但是不能穿过血脑屏障。
包裝
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他說明
Sales restrictions may apply.
訊號詞
Danger
危險分類
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Jessica Kåhlin et al.
Experimental physiology, 99(8), 1089-1098 (2014-06-03)
Studies on experimental animals established that the carotid bodies are sensory organs for detecting arterial blood O2 levels and that the ensuing chemosensory reflex is a major regulator of cardiorespiratory functions during hypoxia. However, little information is available on the
Seham Mustafa et al.
Urology, 84(6), 1549-1549 (2014-12-03)
To examine the effects of neostigmine, an acetylcholinesterase inhibitor that has been used to treat impaired bladder emptying on diabetic rat urinary bladder smooth muscle. Rat urinary detrusor muscle strips were suspended in organ baths containing Krebs' solution for isometric
Machika Moriya et al.
Masui. The Japanese journal of anesthesiology, 63(4), 418-422 (2014-05-03)
We experienced severe asthmatic crisis during general anesthesia in a 45-year-old man with IgG4-related disease, COPD and athma undergoing removal of submandibular gland. The ventilatiory failure was caused by the stimulation of the operation, sputum, and neostigmine. His serum IgG4
Su-Hsun Liu et al.
Clinical toxicology (Philadelphia, Pa.), 53(1), 13-21 (2014-11-21)
Pufferfish-associated tetrodotoxin poisoning occurs occasionally in coastal regions of Asian countries and sporadically elsewhere. While anecdotal reports have suggested neostigmine use, evidence for its clinical effectiveness remains unclear. We sought to determine whether neostigmine was likely to be effective in
H S Bawaskar et al.
Tropical doctor, 44(2), 82-85 (2014-02-20)
Between January 2005 and August 2011 141 victims of krait bite poisoning were admitted to the general hospital at Mahad. Clinical signs and symptoms preceding the development of neuroparalysis were analyzed. Fifty-six percent of patients were male. A total of
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