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Merck
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文件

C1528

Supelco

可卡因 盐酸盐 溶液

1.0 mg/mL in methanol, analytical standard, for drug analysis

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About This Item

经验公式（希尔记法）:
C17H21NO4 · HCl
CAS号:
53-21-4
分子量:
339.81
MDL號碼:
MFCD00058119
分類程式碼代碼:
41116107
PubChem物質ID:
329774894
NACRES:
NA.24

等級

analytical standard, for drug analysis

品質等級

200

drug control

Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

濃度

1.0 mg/mL in methanol

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3

InChI

1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1

InChI 密鑰

PIQVDUKEQYOJNR-VZXSFKIWSA-N

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一般說明

可卡因通常以盐酸可卡因的形式获得，它是白色至类白色粉末。它是通过鼻内途径服用的。在某些手术中用作局部麻醉药物。

應用

使用盐酸可卡因溶液作为校准标准品，使用气相色谱/质谱法（GC/MS）测定人发样品中的可卡因。可作为dragendorff试剂结合纸喷雾电离质谱法定量分析可卡因及其掺杂物如利多卡因和livamisole的标准品。

其他說明

有关合适的仪器技术的更多信息，请参阅产品′分析证书。想要获得更多支持，请联系技术服务部。

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

51.8 °F - closed cup

閃點（°C）

11 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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分析证书(COA)

Lot/Batch Number
0000380989
0000368828
0000368828
0000380989
0000356564

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Quantification of cocaine and its adulterants (lidocaine and levamisole) using the Dragendorff reagent allied to paper spray ionization mass spectrometry
Santos.H, et al.
Analytical Methods : Advancing Methods and Applications (2017)
L Skender et al.
Forensic science international, 125(2-3), 120-126 (2002-03-23)
Hair of young subjects (N = 36) suspected for drug abuse was analysed for morphine, codeine, heroin, 6-acetylmorphine, cocaine, methadone, amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxyethylamphetamine (MDEA). The analysis of morphine, codeine, heroin, 6-acetylmorphine, cocaine, and methadone in
Billy T Chen et al.
Nature, 496(7445), 359-362 (2013-04-05)
Loss of control over harmful drug seeking is one of the most intractable aspects of addiction, as human substance abusers continue to pursue drugs despite incurring significant negative consequences. Human studies have suggested that deficits in prefrontal cortical function and
John W Muschamp et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), E1648-E1655 (2014-04-08)
Hypocretin (orexin) and dynorphin are neuropeptides with opposing actions on motivated behavior. Orexin is implicated in states of arousal and reward, whereas dynorphin is implicated in depressive-like states. We show that, despite their opposing actions, these peptides are packaged in
Thomas C Jhou et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(17), 7501-7512 (2013-04-26)
Many strong rewards, including abused drugs, also produce aversive effects that are poorly understood. For example, cocaine can produce aversive conditioning after its rewarding effects have dissipated, consistent with opponent process theory, but the neural mechanisms involved are not well
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实验方案

HPLC Analysis of Drugs on Ascentis® Express HILIC

Analytical standards for drug analysis including heroin, cocaine, amphetamine, and methylenedioxymethamphetamine.

HPLC Analysis of Drugs on Ascentis® Express HILIC

Analytical standards for drug analysis including heroin, cocaine, amphetamine, and methylenedioxymethamphetamine.

HPLC Analysis of Drugs on Ascentis® Express HILIC

Analytical standards for drug analysis including heroin, cocaine, amphetamine, and methylenedioxymethamphetamine.

HPLC Analysis of Drugs on Ascentis® Express HILIC

Analytical standards for drug analysis including heroin, cocaine, amphetamine, and methylenedioxymethamphetamine.

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