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Merck

82270

Sigma-Aldrich

1,2-二氯丙烷

99%

别名:

二氯化丙烯

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About This Item

线性分子式:
CH3CHClCH2Cl
CAS号:
分子量:
112.99
Beilstein:
1718880
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

3.89 (vs air)

品質等級

蒸汽壓力

40 mmHg ( 19.4 °C)

化驗

99%

形狀

liquid

自燃溫度

1035 °F

expl. lim.

14.5 %

折射率

n20/D 1.439 (lit.)
n20/D 1.439

bp

95-96 °C (lit.)

mp

−100 °C (lit.)

密度

1.156 g/mL at 25 °C (lit.)

SMILES 字串

CC(Cl)CCl

InChI

1S/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3

InChI 密鑰

KNKRKFALVUDBJE-UHFFFAOYSA-N

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應用

1,2-二氯丙烷可用作合成以下物质的结构单元:
  • 在乙磺酸钠的参与下,与二硫化碳和活性亚甲基化合物通过一锅反应合成的2-烯基-1,3-二噻茂烷衍生物。      
  • β与硫醇的可控脱氯偶联反应制备的氯丙基硫化合物。      
  • 在磷叶立德催化的条件下,与 β-酮基硫代酰胺通过[3+2]和[3+3]环化反应制备的噻唑烷和1,3-噻嗪烷衍生物。

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

59.0 °F - closed cup

閃點(°C)

15.0 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

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Synthesis of some 2-ylidene-1, 3-dithiolanes
Lipin KV, et al.
Russ. J. Org. Chem., 53(1), 147-149 (2017)
Monish Arbaz Ansari et al.
Organic & biomolecular chemistry, 17(41), 9151-9162 (2019-10-09)
Phosphonium ylides are being reported here as a catalyst for the formation of thiazolidines and 1,3-thiazinanes from β-ketothioamides (which act as a three atom N, C, and S synthon) with dihaloalkanes via [3 + 2] and [3 + 3] annulations
Divergent Electrolysis for the Controllable Coupling of Thiols with 1, 2-Dichloroethane: a Mild Approach to Sulfide and Sulfoxide
Ling F, et al.
Green Chemistry (2022)
J C Hage et al.
Applied microbiology and biotechnology, 57(4), 548-554 (2002-01-05)
Pseudomonas sp. strain DCA1, which is capable of utilizing 1,2-dichloroethane (DCA) as sole carbon and energy source, was used to oxidize chlorinated methanes, ethanes, propanes, and ethenes. Chloroacetic acid, an intermediate in the DCA degradation pathway of strain DCA1, was
A Trevisan et al.
Archives of toxicology, 66(9), 641-645 (1992-01-01)
Sex- and age-related nephrotoxicity due to 1,2-dichloropropane was studied in vitro by means of renal cortical slices obtained from Wistar rats. Reduced glutathione content, organic anion accumulation (p-aminohippurate), and release of malondialdehyde (to measure the extent of lipid peroxidation), aspartate

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