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Merck

51964

Supelco

缬草烯酸

analytical standard

别名:

(2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-六氢-3,7-二甲基-1H-茚-4-基]-2-甲基-2-丙烯酸

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About This Item

经验公式(希尔记法):
C15H22O2
CAS号:
分子量:
234.33
Beilstein:
3138020
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥98.0% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

cleaning products
cosmetics
food and beverages
personal care

形式

neat

儲存溫度

−20°C

SMILES 字串

[H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI

1S/C15H22O2/c1-9-4-6-12(8-11(3)15(16)17)14-10(2)5-7-13(9)14/h8-9,12-13H,4-7H2,1-3H3,(H,16,17)/b11-8+/t9-,12+,13-/m1/s1

InChI 密鑰

FEBNTWHYQKGEIQ-SUKRRCERSA-N

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一般說明

缬草烯酸是一种具有生物活性的倍半萜烯类化合物,是从缬草属植物中分离得到的天然产物。由于它是 GABA A 受体的有效调节剂,因此可用于治疗多种中枢神经系统功能障碍。

應用

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

其他說明

缬草属的成分

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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其他客户在看

P J Houghton
The Journal of pharmacy and pharmacology, 51(5), 505-512 (1999-07-20)
The underground organs of members of the genus Valeriana (Valerianaceae), as well as related genera such as Nardostachys, are used in the traditional medicine of many cultures as mild sedatives and tranquillizers and to aid the induction of sleep. V.
Total synthesis of valerenic acid, a potent GABAA receptor modulator
Ramharter J and Mulzer J
Organic Letters, 11, 1151-1153 (2009)
S Khom et al.
British journal of pharmacology, 161(1), 65-78 (2010-08-20)
Subunit-specific modulators of gamma-aminobutyric acid (GABA) type A (GABA(A)) receptors can help to assess the physiological function of receptors with different subunit composition and also provide the basis for the development of new drugs. Valerenic acid (VA) was recently identified
Jürgen Ramharter et al.
Organic letters, 11(5), 1151-1153 (2009-01-31)
The first total synthesis of the sesquiterpenoid valerenic acid, a constituent of Valeriana officinalis, is described. The compound is a potent modulator of the GABA(A) receptor and may thus be useful in the treatment of various dysfunctions of the central
Chethan Sampath et al.
Planta medica, 78(6), 575-581 (2012-03-14)
Valerenic acid (VA), a sesquiterpenoid, is one of the major secondary bioactive metabolites of VALERIANA OFFICINALIS L. Until now IN VIVO studies on the absorption, bioavailability, disposition, and metabolism of VA are limited. We established and validated an LC-MS/MS assay

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