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About This Item
经验公式（希尔记法）:
C15H17ClN2O2
CAS号:
分子量:
292.76
Beilstein:
618020
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
产品线
PESTANAL®
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
NMR: suitable
gas chromatography (GC): suitable
mp
96-100 °C
适用性
passes test for identity (NMR)
应用
agriculture
environmental
包装形式
neat
SMILES字符串
CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n2ccnc2
InChI
1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3
InChI key
OWEGWHBOCFMBLP-UHFFFAOYSA-N
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一般描述
氯咪巴唑(Climbazole)是咪唑类抗真菌剂，由于可抑制微生物生长和保护头皮屏障而广泛用作抗头屑(AD)洗发水的活性成分。
应用
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
此氯咪巴唑可作为参考标准品，用于通过超高效液相色谱-串联质谱(UHPLC-MS-MS)测定环境样品和去屑洗发水样品中的氯咪巴唑。
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法律信息
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
C Coiffard et al.
Annales pharmaceutiques francaises, 57(5), 392-396 (1999-10-16)
We compared thermostability of various natural (sulfoprolamine and sodium usnate) or synthetic (climbazol and piroctone olamine) antidandruff agents in aqueous diluted solution at pH around 7. Thermodegradation of these solutions was studied by an isothermal method in thermostatically controlled ovens
Y Kobayashi et al.
The Journal of toxicological sciences, 26(3), 141-150 (2001-09-13)
We examined the effect of climbazole on the induction of rat hepatic microsomal cytochrome P450 (P450), and compared the induction potency with other N-substituted azole drugs such as clorimazole. We found that climbazole is found to be a potent inducer
Yasuna Kobayashi et al.
Biological & pharmaceutical bulletin, 25(1), 53-57 (2002-02-05)
To determine the effect of climbazole on hepatic microsomal cytochrome P450 (P450) and drug-metabolizing enzymes, four different P450 isoforms (CYP2B1, 3A2, 2E1, and 2C12) were examined in female Long-Evans rats. Treatment of rats with climbazole resulted in the induction of
Yan-Wei Yang et al.
Wei sheng yan jiu = Journal of hygiene research, 34(5), 626-628 (2005-12-07)
A high performance liquid chromatography method was established for determination of antidangdruff agent salicylic acid,zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo on a C18 column using acetonitrile-metholaqueous solution (10 mmol/L KH2 PO4 and 5 mmol/L EDTANa2, pH is adjusted
Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography--tandem mass spectrometry
Chen F-Z, et al.
Analytical and Bioanalytical Chemistry, 404(10), 3175-3188 (2012)
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