推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
7D1.13, monoclonal
物種活性
human
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunohistochemistry (frozen sections): suitable
同型
IgG1κ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... BGLAP(632)
一般說明
Osteocalcin is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. In addition, osteocalcin is one of the most abundant, non-collagenous proteins found in mineralized adult bone. Osteocalcin is often studied in the osteogenesis of embryonic and mesenchymal stem cells.
免疫原
KLH-conjugated linear peptide corresponding to Human Osteocalcin.
應用
Detect Osteocalcin using this mouse monoclonal antibody, Anti-Osteocalcin Antibody, Clone 7D1.13 validated for use in IHC (Paraffin) & IHC (tissue).
Research Sub Category
Mesenchymal Stem Cells
Osteobiology
Mesenchymal Stem Cells
Osteobiology
品質
Evaluated by Immunohistochemistry on human trabecular bone in a human bone biopsy.
Immunohistochemical Analysis: A 1:50 Dilution of this antibody detected osteocalcin on human trabecular bone in a human bone biopsy.
Immunohistochemical Analysis: A 1:50 Dilution of this antibody detected osteocalcin on human trabecular bone in a human bone biopsy.
標靶描述
~6 kDa calculated
聯結
Replaces: MABD182
外觀
Format: Purified
分析報告
Control
Human trabecular bone in a human bone biopsy.
Human trabecular bone in a human bone biopsy.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Hao Cheng et al.
Acta biomaterialia, 69, 342-351 (2018-01-26)
The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca10(PO4)6(OH)2) and whitlockite (WH: Ca18Mg2(HPO4)2(PO4)12) minerals, where the WH phase occupies up to 20-35% of total weight. These two bone minerals have different crystal structures and physicochemical properties
Stylianos Kosmidis et al.
Cell reports, 25(4), 959-973 (2018-10-26)
Precisely deciphering the molecular mechanisms of age-related memory loss is crucial to create appropriate therapeutic interventions. We have previously shown that the histone-binding protein RbAp48/Rbbp4 is a molecular determinant of Age-Related Memory Loss. By exploring how this protein regulates the
Zhe Shi et al.
International journal of nanomedicine, 16, 5603-5619 (2021-08-26)
Given that autologous bone graft for bone defects is limited by insufficient supply and morbidity at the donor site, developing biomimetic graft materials as an alternative has gained consistent attention. However, obstacles in designing bone-mimetic materials that could integrate the
Zhe Shi et al.
International journal of nanomedicine, 15, 9337-9353 (2020-12-03)
Autologous bone grafts are the gold standard for treating bone defects. However, limited bone supply and morbidity at the donor site restrict its extensive use. Therefore, developing bone graft materials as an alternative to autologous grafts has gained considerable attention.
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