MABC971

Anti-Kallikrein-13/KLK13 Antibody, clone 33.1

clone 33.1, from mouse

• 别名: Kallikrein-13, Kallikrein-like protein 4, KLK-L4
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 33.1, monoclonal
• 物種活性: human
• 技術: ELISA: suitable; immunohistochemistry: suitable
• 同型: IgG1κ
• NCBI登錄號: NP_056411
• UniProt登錄號: Q9UKR3
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KLK13(26085)

说明

一般說明

Kallikreins-related peptidases (KLKs) are proteases that are important for the desquamation process of the skin (cell shedding). Kallikreins are also associated with carcinogenesis and some serve as a novel cancer and other disease biomarkers. Kallikrein-13/KLK13 is important in lung cancer by allowing lung adenocarcinoma spreading through promoting the expression of various adhesion molecules and it in assisting in extracellular matrix protein degradation necessary for movement. Kallikrein-13/KLK13 also plays a role in salivary tumors and ovarian cancer as well as other cancers in a similar fashion. In both normal and cancerous tissues, Kallikrein-13/KLK13 is secreted into the ECM and expressed in many tissues in both the embryo and adult.

免疫原

Recombinant protein corresponding to Human Kallikrein-13/KLK13.

應用

Immunohistochemistry Analysis: A representative lot of this antibody detected Kallikrein-13/KLK13 in Normal ovarian surface epithelium and epithelial ovarian cancer tissues (White et al., (2009) British Journal of Cancer. 101:1107-1113).

ELISA: A representative lot of this antibody detected various Kallikrein-13/KLK13 concentrations of several human tissues (Kapadia et al., (2003) Clinical chemistry. 49(1):77–86).

This Anti-Kallikrein-13/KLK13 Antibody, clone 33.1 is validated for use in Immunohistochemistry and ELISA for the detection of Kallikrein-13/KLK13.

品質

Evaluated by Immunohistochemistry in human lung and human prostate tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Kallikrein-13/KLK13 in human prostate tissue.

標靶描述

30 kDa calculated

外觀

Format: Purified

Purified mouse monoclonal IgG1k in 0.1 M Sodium Bicarbonate buffer pH8.2 without preservatives.

其他說明

Concentration: Please refer to lot specific datasheet.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: nwg