推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
83KKII, monoclonal
物種活性
human
製造商／商標名
Chemicon®
技術
ELISA: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
同型
IgG
運輸包裝
wet ice
一般說明
Measles is a highly contagious, acute febrile illness that has been one of the most common viral diseases of young children. Although measles has been effectively controlled in recent years by the use of live attenuated virus vaccines, measles continues to have a serious impact on human health as evidenced by its continued persistence in developing countries. Measles is characterized by a prodrome illness with rapidly rising fever that culminates in a generalized macular-papular rash. The appearance of Koplik′s spots on the mouth epithelium during or after the prodromal phase is pathognomonic for measles. The measles virus belongs to the family Paramyxoviridae, and is a member of the genus Morbillivirus. Measles is an enveloped, pleomorphic virus ranging from 100 to 250 nm in diameter with a single stranded linear RNA. Infected cells contain large amounts of nucleoprotein antigen which is the major internal protein of measles virus. Consequently, the dominant part of the antibody response to measles virus involves the nucleoprotein antigen.
特異性
MAB8906 recognizes the measles nucleoprotein by capture EIA.
免疫原
Epitope: Nucleoprotein
應用
Capture ELISA: A 1:5,000-1:10,000 dilution of a previous lot was used in ELISA.
Indirect Immunofluorescence: A previous lot of this antibody was used on indirect immunofluorescence.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected the measles nucleoprotein in cells infected with measles virus.
Optimal working dilutions must be determined by end user.
Indirect Immunofluorescence: A previous lot of this antibody was used on indirect immunofluorescence.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected the measles nucleoprotein in cells infected with measles virus.
Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
This Anti-Measles Antibody, nucleoprotein, clone 83KKII is validated for use in ELISA, IF for the detection of Measles.
外觀
Protein A purified
Format: Purified
Purified mouse monoclonal IgG in buffer containing liquid in PBS with 0.1% sodium azide.
儲存和穩定性
Stable for 1 year at from date of receipt.
分析報告
Control
Measles Control Slides, Catalogue Number 5031-5
Measles Control Slides, Catalogue Number 5031-5
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Measles virus entry through the signaling lymphocyte activation molecule governs efficacy of mantle cell lymphoma radiovirotherapy.
Miest, TS; Frenzke, M; Cattaneo, R
Molecular Therapy null
Lung involvement in childhood measles: severe immune dysfunction revealed by quantitative immunohistochemistry.
Talib Moyses Moussallem,Fernanda Guedes,Elaine Raniero Fernandes,Carla Pagliari et al.
Human Pathology null
Adherens junction protein nectin-4 is the epithelial receptor for measles virus.
Muhlebach, MD; Mateo, M; Sinn, PL; Prufer, S; Uhlig, KM; Leonard, VH; Navaratnarajah et al.
Nature null
Daria Jacob et al.
PloS one, 9(1), e86658-e86658 (2014-01-30)
Yeasts are largely used as bioreactors for vaccine production. Usually, antigens are produced in yeast then purified and mixed with adjuvants before immunization. However, the purification costs and the safety concerns recently raised by the use of new adjuvants argue
Ludmila Perelygina et al.
Frontiers in immunology, 12, 796065-796065 (2022-01-11)
Rubella virus (RuV) has recently been found in association with granulomatous inflammation of the skin and several internal organs in patients with inborn errors of immunity (IEI). The cellular tropism and molecular mechanisms of RuV persistence and pathogenesis in select
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