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Merck
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主要文件

MAB5504

Sigma-Aldrich

抗-囊泡谷氨酸转运体2抗体

clone 8G9.2, Chemicon®, from mouse

别名:

VGLUT2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

8G9.2, monoclonal

种属反应性

mouse, rat

种属反应性（根据同源性预测）

human

制造商/商品名称

Chemicon®

技术

immunohistochemistry: suitable
western blot: suitable

同位素/亚型

IgG1

NCBI登记号

NM_020346.1

UniProt登记号

Q9JI12

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... SLC17A6(57084)

一般描述

囊泡谷氨酸转运蛋白2（VGLUT2）是一种钠依赖性无机磷酸盐共转运蛋白，参与星形胶质细胞释放钙依赖性谷氨酸。它在表现出经典兴奋性特征的突触中仅在位于突触小泡的神经元子集中表达。在缺乏VGLUT1的大脑区域中发现了VGLUT2 mRNA，VGLUT1是一种相关蛋白，也显示出钠依赖性无机磷酸盐共转运蛋白活性。

特异性

与VGLUT2（囊泡谷氨酸转运蛋白2）反应。

应用

使用经验证可用于WB、IH的抗囊泡谷氨酸转运蛋白2抗体检测囊泡谷氨酸转运蛋白2。
免疫组织化学： 一个先前批次以1:50-1:300稀释度在浮动小鼠脑切片上使用ABC和NiDAB起作用。

最佳工作稀释度必须由最终用户确定。

质量

通过蛋白质印迹法对小鼠脑裂解物进行评价。

蛋白质印迹分析： 该抗体以1:500稀释度在10 µg小鼠脑裂解物中检测到VGLUT2。

目标描述

56 kDa

外形

小鼠单克隆抗体，溶于含0.1%叠氮化钠的PBS中。
形式：纯化

其他说明

浓度：关于批次特定浓度请参见检验报告。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

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I Pose et al.
Neuroscience, 172, 246-255 (2010-11-04)
The rostral ventro-medial medullary reticular formation is a complex structure that is involved with a variety of motor functions. It contains glycinergic neurons that are activated during active (rapid eye movement (REM)) sleep (AS); these neurons appear to be responsible
Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum.
Ebner, BA; Ingram, MA; Barnes, JA; Duvick, LA; Frisch, JL; Clark, HB; Zoghbi, HY; Ebner, TJ; Orr, HT
The Journal of Neuroscience null
SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.
Duvick, L; Barnes, J; Ebner, B; Agrawal, S; Andresen, M; Lim, J; Giesler, GJ; Zoghbi, HY; Orr, HT
Neuron null
Peiyan Wong et al.
The Journal of comparative neurology, 510(4), 440-461 (2008-07-31)
The temporal cortex of grey squirrels contains three architectonically distinct regions. One of these regions, the temporal anterior (Ta) region has been identified in previous physiological and anatomical studies as containing several areas that are largely auditory in function. Consistent
Chia-Chi Liao et al.
The Journal of comparative neurology, 524(7), 1494-1526 (2015-11-01)
A complete unilateral lesion of the dorsal column somatosensory pathway in the upper cervical spinal cord deactivates neurons in the hand region in contralateral somatosensory cortex (areas 3b and 1). Over weeks to months of recovery, parts of the hand
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