MAB3828

Anti-Mucin 5B Antibody, clone 15.5B

clone 15.5B, Chemicon^®, from mouse

• 别名: MUC5B
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 15.5B, monoclonal
• 物種活性: human, monkey
• 製造商／商標名: Chemicon^®
• 技術: ELISA: suitable; immunohistochemistry: suitable; western blot: suitable
• 同型: IgG2b
• NCBI登錄號: NM_002458.1
• UniProt登錄號: Q9HC84
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MUC5B(727897)

说明

一般說明

Mucins are a family of highly glycosylated proteins that are present on the surface of, and are secreted by, many glandular epithelial cells. Mucins provide a barrier between the luminal membranes of cells in the epithelium and their environment. For instance, in the digestive tract, the mucin barrier protects the epithelial cells from the action of proteolytic enzymes. These high molecular weight glycoproteins consist of a nonglobular protein backbone (apomucin) and many O-linked glycans. Salivary Mucin 5B proteins are some of the largest polypeptides, with molecular weights ranging from 14 - 40 x 10³ kDa.

特異性

Reacts with Mucin 5B (MUC5B). Does not react with human Mucin 5A or 5C.

免疫原

Un-glycosylated, serine- and threonine-free synthetic peptide from the central region of human MUC5B.

應用

Research Category
Apoptosis & Cancer

Research Sub Category
Tumor Markers

This Anti-Mucin 5B Antibody, clone 15.5B is validated for use in ELISA, WB, IH for the detection of Mucin 5B.

Western blot: Bands in the high molecular weight range of 200kDa or above are expected for highly glycosylated proteins.

Immunohistchemistry: Paraffin sections. Deglycosylating the tissue is critical to expose epitope. There are a number of deglycosylation protocols available and a discussion of these related to Mucin can be found in Cao, Y. et al. (1997)(see references).

ELISA

Optimal working dilutions must be determined by end user.

外觀

Format: Purified

Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide.

儲存和穩定性

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable