推荐产品
生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
human
技術
immunocytochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... TNS3(64759)
一般說明
Tensin-3 is a member of the Tensin family of proteins that serve as a connection between the cytoskeleton and extracellular matrix. Because of this link, Tensin’s are commonly thought to regulate signaling for the shape of the cell and motility. Tensin-3 localizes in the cell cytoplasm and has been shown to be significantly decreased in many different human cancer cell lines. Higher expression levels of Tensin-3 were also found to be associated with longer survival. Tensin-3 has also been found to be highly expressed in functioning thyroid follicular adenomas while expression is significantly lower in non-functioning thyroid follicular adenomas, which seems to imply that Tensin-3 has an important role in basic thyroid function.
免疫原
KLH-conjugated linear peptide corresponding to human Tensin-3.
應用
Anti-Tensin-3 Antibody detects level of Tensin-3 & has been published & validated for use in WB & IC.
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Tensin-3 in A431 cells.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
Cytoskeleton
ECM Proteins
Cytoskeleton
品質
Evaluated by Western Blot in human kidney tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Tensin-3 in 10 µg of human kidney tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Tensin-3 in 10 µg of human kidney tissue lysate.
標靶描述
~180 kDa observed.
The calculated molecular weight is 155 kDa, however Tensin-3 has been shown as a ~180 kDa band in western blots (Cui, Y., et al. (2004). Molecular Cancer Research. 2:225–232).
An uncharacterized band appears at ~22 kDa in some lysates.
The calculated molecular weight is 155 kDa, however Tensin-3 has been shown as a ~180 kDa band in western blots (Cui, Y., et al. (2004). Molecular Cancer Research. 2:225–232).
An uncharacterized band appears at ~22 kDa in some lysates.
外觀
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
分析報告
Control
Human kidney tissue lysate
Human kidney tissue lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Astrid Veß et al.
Journal of cell science, 130(13), 2172-2184 (2017-05-19)
A change regarding the extent of adhesion - hereafter referred to as adhesion plasticity - between adhesive and less-adhesive states of mammalian cells is important for their behavior. To investigate adhesion plasticity, we have selected a stable isogenic subpopulation of
Nuria Barber-Pérez et al.
Journal of cell science, 133(12) (2020-05-13)
Fibrillar adhesions are important structural and adhesive components in fibroblasts, and are required for fibronectin fibrillogenesis. While nascent and focal adhesions are known to respond to mechanical cues, the mechanoresponsive nature of fibrillar adhesions remains unclear. Here, we used ratiometric
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