推荐产品
生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
rat, human
製造商／商標名
Chemicon®
技術
western blot: suitable
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... CLTA(1211)
特異性
Clathrin light chain a and b variants (CLC). By Western blot the antibody recognizes a doublet at ~35-40 kDa on rat brain extracts.
應用
This Anti-Clathrin Light Chain Antibody is validated for use in WB for the detection of Clathrin Light Chain.
Western blot: 1:50,000-1:100,000 on rat brain extracts.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
標靶描述
~35-40 kDa
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Fan Fan et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(32) (2021-08-08)
Pancreatic β cells operate with a high rate of membrane recycling for insulin secretion, yet endocytosis in these cells is not fully understood. We investigate this process in mature mouse β cells by genetically deleting dynamin GTPase, the membrane fission
Kazuki Obashi et al.
Nature communications, 14(1), 732-732 (2023-02-10)
Conformational changes in endocytic proteins are regulators of clathrin-mediated endocytosis. Three clathrin heavy chains associated with clathrin light chains (CLC) assemble into triskelia that link into a geometric lattice that curves to drive endocytosis. Structural changes in CLC have been
Yang Yang et al.
Developmental cell, 43(4), 507-521 (2017-11-22)
Assembly of the endocytic machinery is a constitutively active process that is important for the organization of the plasma membrane, signal transduction, and membrane trafficking. Existing research has focused on the stochastic nature of endocytosis. Here, we report the emergence
Stephanie A Zlatic et al.
Molecular biology of the cell, 24(15), 2378-2388 (2013-06-14)
A role for clathrin in AP-3-dependent vesicle biogenesis has been inferred from biochemical interactions and colocalization between this adaptor and clathrin. The functionality of these molecular associations, however, is controversial. We comprehensively explore the role of clathrin in AP-3-dependent vesicle
Mian Cao et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(49), 16544-16549 (2014-12-05)
Several proteins encoded by PD genes are implicated in synaptic vesicle traffic. Endophilin, a key factor in the endocytosis of synaptic vesicles, was shown to bind to, and be ubiquitinated by, the PD-linked E3 ubiquitin ligase Parkin. Here we report
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