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420355

Sigma-Aldrich

Isoprenaline hydrochloride

≥99% (TLC), solid, β-adrenoceptor agonist, Calbiochem

别名:

盐酸异丙肾上腺素

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About This Item

经验公式（希尔记法）:
C11H17NO3 · xHCl
CAS号:
51-30-9
分子量:
211.26 (free base basis)
MDL號碼:
MFCD00012603
分類程式碼代碼:
12352200
NACRES:
NA.77

product name

盐酸异丙肾上腺素, Phenethylamine derivative.

品質等級

100

化驗

≥99% (TLC)

形狀

solid

製造商／商標名

Calbiochem®

儲存條件

OK to freeze
protect from light

顏色

white to off-white
 white

溶解度

ethanol: soluble
water: soluble

運輸包裝

ambient

儲存溫度

10-30°C

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI 密鑰

IROWCYIEJAOFOW-UHFFFAOYSA-N

一般說明

苯乙胺衍生物。一种刺激腺苷酸环化酶活性的选择性β-肾上腺素能激动剂。促进糖原分解并引起支气管扩张。通过产生一氧化氮增加兔气管细胞中Cl–的扩散和电位差。据报道，通过Rap1和B-Raf依赖性过程激活MAP激酶（ERK）。
苯乙胺衍生物。一种增加胞质cAMP的选择性β-肾上腺素能激动剂。促进糖原分解并引起支气管扩张。通过产生一氧化氮增加兔气管细胞中Cl-的扩散和电位差。

生化／生理作用

主要靶标
β肾上腺素能激动剂
产物不与ATP竞争。
可逆：否
细胞渗透性：否

警告

毒性：刺激性（B）

重構

溶液中不稳定；仅在使用前进行复溶。

其他說明

Schmitt, J.M., and Stork, P.J.2000.J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997.Prostate 33, 46.
Takemura, H., et al. 1995.J. Pharmacol.Exp.Ther.274, 584.
Kishimoto, I., et al. 1994.J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994.Mol.Cell Biochem.141, 27.
Yashiro, K., et al. 1994.J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993.J. Neurochem.60, 260.
von Zastrow, M., et al. 1993.J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985.J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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