推荐产品
生物源
synthetic
品質等級
產品線
EMPROVE® EXPERT
bp
360 °C (lit.)
mp
147-149 °C (lit.)
密度
1.067 g/mL at 25 °C (lit.)
應用
pharma/biopharma processes
pharmaceutical
儲存溫度
15-25°C
SMILES 字串
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI 密鑰
HVYWMOMLDIMFJA-DPAQBDIFSA-N
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一般說明
SyntheCho® Synthetic Cholesterol, for Cell Culture Emprove® Expert, isa synthetic cholesterol supplement that has been developed to specifically meetthe demands of the life science and biopharmaceutical industries. Due to thesynthetic nature of the material, the elimination of animal-derived componentsreduces the incidence of performance variability in the medium and eliminatessafety risks due to adventitious agents associated with these components. Witha newly optimized manufacturing process, this product is available inquantities from grams to tons to support your development progress.
應用
This supplement is designed to be added to our chemically defined,animal component-free CHO and insect (Sf-RVN) cell media, as well as HEK-293media for VGT manufacturing. This material has been tested for compatibilitywith CHO and Sf-9 cell lines. Cholesterol provides structure to cellularmembranes, stores energy, and is vital in cell signaling and in regulating cellfunctions.
This product is intended for research or further manufacturing but notfor human or therapeutic use.
This product is intended for research or further manufacturing but notfor human or therapeutic use.
生化/生理作用
所有生物膜的主要成分;总脑脂质中约25%为胆固醇。
包裝
137672.0001 /1g /
137672.0010 / 10 g /
137672.0100 / 100 g /
137672.1000 / 1000g /
137672.0010 / 10 g /
137672.0100 / 100 g /
137672.1000 / 1000g /
法律資訊
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Cell, 171(5), 1094-1109 (2017-11-18)
Cholesterol is a critical nutrient requiring tight constraint in the endoplasmic reticulum (ER) due to its uniquely challenging biophysical properties. While the mechanisms by which the ER defends against cholesterol insufficiency are well described, it remains unclear how the ER senses
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