推荐产品
ligand
(Trimethylammoniumethyl)
物料
polypropylene housing
产品线
Eshmuno®
表单
prepacked column
参数
≤8 bar pressure
1000 cm/hr max. flow rate
床长度
100 mm
柱床体积
5 mL
色谱柱内径
8 mm
体积
5 mL
基质活性基团
Polyvinyl Ether
平均粒径
85 μm
容量
~150 mg, BSA binding capacity
应用
mAb
recombinant protein
vaccine development
分离技术
anion exchange
储存温度
15-25°C
一般描述
8 x 100mm
MiniChrom Pre-packed Columns with Eshmuno® cation exchange resin is designed for the rapid evaluation of resins for bioprocess development. The results obtained for biomolecule separations are generally comparable to the results achieved using laboratory-scale columns (e.g. 100 x 16 mm ID).
In bioprocess design, the MiniChrom columns can be used to rapidly determine whether a target biomolecule is bound to and can be eluted from the Eshmuno® resin, as well as determine whether an appropriate target yield may be achieved and whether major contaminants could potentially be removed.
MiniChrom columns are designed for process development, method optimization and parameter screening as well as sample preparation. MiniChrom columns are quality checked for HETP and asymmetry, providing superior reproducibility, excellent scalability, convenient comparison of different chromatography media.
MiniChrom columns are made from biocompatible polypropylene (PP) and polyethylene (PE) and are available in 1 and 5 mL bed volumes. The 8mm diameter columns allow for scale-up from 1 to 5mL column volumes, with a constant internal diameter. These columns are compatible with any chromatographic work station, HPLC system or peristaltic pump.
In bioprocess design, the MiniChrom columns can be used to rapidly determine whether a target biomolecule is bound to and can be eluted from the Eshmuno® resin, as well as determine whether an appropriate target yield may be achieved and whether major contaminants could potentially be removed.
MiniChrom columns are designed for process development, method optimization and parameter screening as well as sample preparation. MiniChrom columns are quality checked for HETP and asymmetry, providing superior reproducibility, excellent scalability, convenient comparison of different chromatography media.
MiniChrom columns are made from biocompatible polypropylene (PP) and polyethylene (PE) and are available in 1 and 5 mL bed volumes. The 8mm diameter columns allow for scale-up from 1 to 5mL column volumes, with a constant internal diameter. These columns are compatible with any chromatographic work station, HPLC system or peristaltic pump.
特点和优势
Eshmuno® Q chromatography resin enables:
Superior productivity for downstream processing of biomolecules
- Purification of acidic and neutral proteins and peptides from different sources, including plasma
Superior productivity for downstream processing of biomolecules
- High flow rate versus pressure-flow behavior
- Excellent removal of impurities, such as HCP, leached Protein A, and viruses
- Robust and safe packing procedures
- Strong chemical stability
法律信息
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
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