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Merck
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Key Documents

07-601

Sigma-Aldrich

抗TTF-1抗体

serum, Upstate®

别名:

Anti-BCH, Anti-BHC, Anti-NK-2, Anti-NKX2.1, Anti-NKX2A, Anti-NMTC1, Anti-T/EBP, Anti-TEBP, Anti-TITF1, Anti-TTF-1, Anti-TTF1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, rat, human

製造商/商標名

Upstate®

技術

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... A1CF(29974)

特異性

TTF-1

免疫原

对应于全长TTF-1的6His融合蛋白(甲状腺转录因子1,也称为甲状腺核因子1,同源盒蛋白Nkx-2.1)

應用

抗TTF-1抗体是一种高质量的兔多克隆抗体,用于检测TTF-1,&已在IP、WB & IHC中得到验证。
研究子类别
转录因子
研究类别
表观遗传学&核功能

品質

通过免疫印迹法对H441人肺上皮细胞的核提取物进行了常规评估

標靶描述

42kDa

聯結

替代:MABE513

外觀

兔抗血清,含有0.05%叠氮化钠,然后添加甘油至30%
血清

儲存和穩定性

在-20°C下可保存2年

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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A Khoor et al.
Human pathology, 30(6), 695-700 (1999-06-22)
Differentiation of malignant mesothelioma from adenocarcinoma, particularly from a lung primary, remains a difficult diagnostic problem. Surfactant protein B precursor (pro-SP-B) and thyroid transcription factor 1 (ITF-1) are expressed selectively in the normal respiratory epithelium and in adenocarcinomas of the
R J Bohinski et al.
Journal of neuro-oncology, 40(3), 227-231 (1999-03-05)
Determining the primary site of a cerebral metastatic adenocarcinoma is complicated by the histologic similarity of most adenocarcinomas. Thyroid Transcription Factor-1 (TTF-1) is a highly specific marker of peripheral airway cell neoplasms. Formalin fixed tissue from 30 patients with brain
Eric P Knott et al.
Cells, 13(13) (2024-07-12)
Understanding tumor-host immune interactions and the mechanisms of lung cancer response to immunotherapy is crucial. Current preclinical models used to study this often fall short of capturing the complexities of human lung cancer and lead to inconclusive results. To bridge
Mario DeFelice et al.
The Journal of biological chemistry, 278(37), 35574-35583 (2003-06-28)
Thyroid transcription factor-1 (TTF-1) is a 43-kDa, phosphorylated member of the Nkx2 family of homeodomain-containing proteins expressed selectively in lung, thyroid, and the central nervous system. To assess the role of TTF-1 and its phosphorylation during lung morphogenesis, mice bearing
Karine Pozo et al.
iScience, 24(9), 102953-102953 (2021-09-02)
Lineage-defining transcription factors (LTFs) play key roles in small-cell lung cancer (SCLC) pathophysiology. Delineating the LTF-regulated genes operative in SCLC could provide a road map to identify SCLC dependencies. We integrated chromatin landscape and transcriptome analyses of patient-derived SCLC preclinical

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