07-436-AF488

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate

0.5 mg/mL, from rabbit

• 别名: Histone H3.1t, H3/t, H3t, H3/g
• UNSPSC代码: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 偶联物: ALEXA FLUOR^™ 488
• 抗体形式: purified antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 种属反应性: human
• 种属反应性（根据同源性预测）: vertebrates (based on 100% sequence homology)
• 浓度: 0.5 mg/mL
• 技术: immunocytochemistry: suitable
• NCBI登记号: NM_003493
• UniProt登记号: Q16695
• 运输: wet ice
• 靶向翻译后修饰: monomethylation (Lys4)
• 基因信息: human ... H3C1(8350)

说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-436.

免疫原

Linear peptide corresponding to Histone H3 monomethylated at Lys4.

应用

This Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).

质量

Evaluated by Immunocytochemisty Analysis in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

目标描述

~17 kDa observed (Refer to Cat. No. 07-436)

外形

Purified rabbit Alexa Fluor^™ 488 conjugated antibody in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.

法律信息

ALEXA FLUOR is a trademark of Life Technologies

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable