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Key Documents

04-811

Sigma-Aldrich

Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

culture supernatant, Upstate®

别名:

NOS III, endothelial nitric oxidase synthase, endothelial nitric oxide synthase, nitric oxide synthase 3 (endothelial cell)

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

monoclonal

物種活性

bovine

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

phosphorylation (pThr495)

基因資訊

mouse ... Nos3(287024)

特異性

Predicted cross-reactivity with human, rabbit, mouse and rat
Recognizes phosphorylated eNOS/NOS III.

免疫原

Peptide containing the sequence KK[pT]FK in which pT corresponds to phosphothreonine at residue 495 of human eNOS/NOS III

應用

This Anti-phospho-eNOS/NOS III (Thr495) Antibody is validated for use in WB for the detection of phospho-eNOS/NOS III (Thr495).
Western Blot Analysis:
A 1:2,000-1:10,000 dilution of this lot detected phosphorylated eNOS/NOS III in fetal bovine heart endothelial cell lysate.

品質

routinely evaluated by immunoblot on fetal bovine heart endothelial cell lysate

標靶描述

135 kDa

聯結

Replaces: 05-811

外觀

Cultured supernatant in 0.05% sodium azide

分析報告

Control
Fetal bovine heart endothelial cell lysate

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yang, T; Shen, JB; Yang, R; Redden, J; Dodge-Kafka, K; Grady, J; Jacobson, KA; Liang, BT
Circulation. Heart Failure null
A P S Mesquita et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 55, e11612-e11612 (2022-02-10)
Anoikis is a type of apoptosis that occurs in response to the loss of adhesion to the extracellular matrix (ECM). Anoikis resistance is a critical mechanism in cancer and contributes to tumor metastasis. Nitric oxide (NO) is frequently upregulated in
Martina Monti et al.
The Journal of pharmacology and experimental therapeutics, 351(3), 500-509 (2014-09-23)
At the cardiovascular level, nitric oxide (NO) controls smooth muscle functions, maintains vascular integrity, and exerts an antihypertensive effect. Metal-nonoates are a recently discovered class of NO donors, with NO release modulated through the complexation of the N-aminoethylpiperazine N-diazeniumdiolate ligand

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