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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 100 μg (with stopper and crimp cap (850151P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850151P-500ug))
製造商／商標名
Avanti Research™ - A Croda Brand 850151P
脂質類型
cardiolipins
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]
一般說明
18:1 PI（5）P（1，2-二油酰基-sn-甘油-3-磷酸-（1′-肌醇-4′-磷酸））是修饰脂质的铵盐，在二油酰基的9th碳上带有一个双键。4-磷酸磷脂酰肌醇（PI-4-P）是质膜中存在的丰富的磷酸肌醇物质。
肌醇磷脂物质是膜结合的信号分子，它参与细胞生理学的几乎所有方面，包括细胞生长、代谢、增殖和存活。
應用
18:1 PI（5）P（1，2-二油酰基-sn-甘油-3-磷酸-（1′-肌醇-4′-磷酸）（铵盐））已用于蛋白质−脂质覆盖测定。它可用于生成脂质体浮选分析用小型单层囊泡。它也可以用于不同的脂质结合特异性研究。
生化／生理作用
4-磷酸磷脂酰肌醇（PI-4-P）是膜运输、极化生长和细胞骨架组织所必需的重要因子。
包裝
带塞子和压接盖的2 mL棕色血清瓶（850151P-100ug）
带塞子和压接盖的2 mL棕色血清瓶（850151P-500ug）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
No data available
閃點（°C）
No data available
Vikram Ghugtyal et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(28), 8644-8649 (2015-07-01)
The phospholipid phosphatidylinositol-4-phosphate [PI(4)P], generated at the Golgi and plasma membrane, has been implicated in many processes, including membrane traffic, yet its role in cell morphology changes, such as the budding to filamentous growth transition, is unknown. We show that
Chao-Yuan Yu et al.
Plant physiology, 183(1), 221-235 (2020-03-25)
Phosphoinositides function as lipid signals in plant development and stress tolerance by binding with partner proteins. We previously reported that Arabidopsis (Arabidopsis thaliana) phosphoinositide-specific phospholipase C2 functions in the endoplasmic reticulum (ER) stress response. However, the underlying molecular mechanisms of
Carolyn M Shirey et al.
Analytical biochemistry, 516, 9-12 (2016-10-28)
To reduce costs of lipid-binding assays, allow for multiple lipids to be screened for protein binding simultaneously, and to make lipid binding more user friendly, lipids have been dotted onto membranes to investigate lipid-protein interactions. These assays are similar to
Mark R Lundquist et al.
Molecular cell, 70(3), 531-544 (2018-05-05)
While the majority of phosphatidylinositol-4, 5-bisphosphate (PI-4, 5-P2) in mammalian cells is generated by the conversion of phosphatidylinositol-4-phosphate (PI-4-P) to PI-4, 5-P2, a small fraction can be made by phosphorylating phosphatidylinositol-5-phosphate (PI-5-P). The physiological relevance of this second pathway is
Lee Dolat et al.
The Journal of cell biology, 214(5), 517-527 (2016-08-24)
Macropinocytosis, the internalization of extracellular fluid and material by plasma membrane ruffles, is critical for antigen presentation, cell metabolism, and signaling. Macropinosomes mature through homotypic and heterotypic fusion with endosomes and ultimately merge with lysosomes. The molecular underpinnings of this
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