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描述
L-α-glycerophosphoryl(choline-d9), water:ethanol (9:1)
化驗
>99% phosphorus (P) basis (qNMR)
形狀
solution
包裝
pkg of 1 × 1 mL (100403X-100ug)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
0.1 mg/mL (100403X-100ug)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.
Glycerophosphocholine (GPC), is a water-soluble deacylated phosphatidylcholine derivative. It is majorly generated from choline based phospholipids associated with membranes. GPC is widely distributed in human blood and saliva. L-α-glycerophosphoryl(choline-d9) (GPC-d9) is the deuterium-labeled form of GPC.
應用
GPC-d9 has been used as an internal standard in ultra-performance liquid chromatograph coupled to a SCIEX 4500QT mass spectrometer (UPLC-MS/MS) for the quantification of choline compounds from whole milk samples.
生化／生理作用
Glycerophosphocholine (GPC) protects mitochondrial respiratory complex I during oxidative stress associated with liver ischemia-reperfusion. GPC is an ergogenic supplement that improves muscle force production. The deuterium-labeled glycerophosphocholine is employed as an internal standard for human milk choline quantification using liquid chromatography-tandem mass spectrometry.
包裝
5 mL Clear Glass Sealed Ampule (100403X-100ug)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance
Marcus L, et al.
Journal of the International Society of Sports Nutrition, 14(1), 39-39 (2017)
Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine
Strifler G, et al.
PLoS ONE, 11(11) (2016)
Phosphatidylcholine biosynthesis in Mitis group streptococci via host metabolite scavenging
Joyce LR, et al.
Journal of Bacteriology, 201(22), e00495-e00419 (2019)
Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine
Strifler G, et al.
Testing, 11(11) (2016)
Total Water-Soluble Choline Concentration Does Not Differ in Milk from Vegan, Vegetarian, and Nonvegetarian Lactating Women
Perrin MT, et al.
The Journal of Nutrition, 11(12), 3024-3024 (2019)
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