推荐产品
化驗
98%
形狀
powder
mp
140-142 °C (lit.)
SMILES 字串
[O-][N+](=O)c1ccc2[nH]ccc2c1
InChI
1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H
InChI 密鑰
OZFPSOBLQZPIAV-UHFFFAOYSA-N
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應用
作为以下制备反应的反应物：
- 具有药物活性的 2-氧代-1-吡咯烷类似物
- 色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚类化合物可作为潜在的抗癌免疫调节剂
- 蛋白激酶抑制剂和抗增殖剂
- 代谢型谷氨酸受体4（mGlu4）的正变构调节剂。
- 抗真菌剂
- 大麻素1型受体（CB1）拮抗剂
- 潜在抗癌剂
- 潜在的抗血管药
- 选择性抗白血病药
- 抗人类免疫缺陷病毒亚型1（HIV-1）的药物
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Dam. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
Wengen Ouyang et al.
Journal of chemical theory and computation, 16(1), 666-676 (2019-12-10)
The importance of many-body dispersion effects in layered materials subjected to high external loads is evaluated. State-of-the-art many-body dispersion density functional theory calculations performed for graphite, hexagonal boron nitride, and their heterostructures were used to fit the parameters of a
D Loakes et al.
Nucleic acids research, 22(20), 4039-4043 (1994-10-11)
4-, 5- and 6-Nitroindole have been investigated and compared with 3-nitropyrrole as universal bases in oligodeoxynucleotides. Of these the 5-nitroindole derivative was found to be superior giving higher duplex stability, and behaving indiscriminately towards each of the four natural bases
D Loakes et al.
Nucleic acids research, 23(13), 2361-2366 (1995-07-11)
3-Nitropyrrole and 5-nitroindole have been assessed as universal bases in primers for dideoxy DNA sequencing and in the polymerase chain reaction (PCR). In contrast to a previous report, we have found that the introduction of more than one 3-nitropyrrole residue
A Kunitsyn et al.
Journal of biomolecular structure & dynamics, 15(3), 597-603 (1998-01-24)
Effect of attachment of 1-(2-deoxy-beta-D-ribofuranosyl)-5-nitroindole (NIDR) to the ends of target sequence of oligonucleotides immobilized on gel micromatrix on stability of duplex formed by hybridization with DNA fragment was studied. It was shown that adjunction of NIDR to 5' as
P M Vallone et al.
Nucleic acids research, 27(17), 3589-3596 (1999-08-14)
Effects of the universal base 5-nitroindole on the thermodynamic stability of DNA hairpins having a 6 bp stem and four base loops were investigated by optical absorbance and differential scanning calorimetry techniques. Melting studies were conducted in buffer containing 115
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