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Merck

H11904

Sigma-Aldrich

2,5-己二醇

99% (mixture of isomers)

别名:

2,5-二羟基己烷

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About This Item

线性分子式:
CH3CH(OH)CH2CH2CH(OH)CH3
CAS号:
分子量:
118.17
Beilstein:
1719248
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

99% (mixture of isomers)

表单

liquid

折射率

n20/D 1.447 (lit.)

沸点

216-218 °C (lit.)

密度

0.961 g/mL at 25 °C (lit.)

SMILES字符串

CC(O)CCC(C)O

InChI

1S/C6H14O2/c1-5(7)3-4-6(2)8/h5-8H,3-4H2,1-2H3

InChI key

OHMBHFSEKCCCBW-UHFFFAOYSA-N

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应用

2,5-Hexanediol can be used as:
  • A reactant to synthesize N-substituted pyrroles by oxidative coupling with primary amines.
  • An alkylating agent to synthesize substituted carbazoles via Friedel-Crafts alkylation with indoles.
  • A monomer in the preparation of polyesters by reacting with diacid chlorides.

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

213.8 °F - closed cup

闪点(°C)

101 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Corey Frazer et al.
Nature microbiology, 5(11), 1374-1389 (2020-07-29)
Cell identity in eukaryotes is controlled by transcriptional regulatory networks that define cell-type-specific gene expression. In the opportunistic fungal pathogen Candida albicans, transcriptional regulatory networks regulate epigenetic switching between two alternative cell states, 'white' and 'opaque', that exhibit distinct host
On the pattern of changes in the rat nervous system produced by 2,5 hexanediol. A topographical study by light microscopy.
J B Cavanagh et al.
Brain : a journal of neurology, 104(2), 297-318 (1981-06-01)
2,5-Hexane diol induced thymic atrophy and lymphocytotoxicity in rats.
K P Singh et al.
Industrial health, 21(4), 235-242 (1983-01-01)
A K Agrawal et al.
Neurotoxicology, 6(3), 53-59 (1985-01-01)
Single exposure of 150, 300 and 600 mg/kg 2,5-hexanediol, (2,5 HD) a metabolite of n-hexane showed no significant effect on 3H-spiroperidol binding to corpus striatal membranes when compared with control animals, where as repeated exposure of 2,5-HD, 300 and 600
K Kannan et al.
Environmental research, 36(1), 14-25 (1985-02-01)
A preliminary study on immunotoxicologic evaluation of 2,5-hexanediol (one of the principal metabolites of n-hexane), involving multiple immunological parameters, was carried out in mice. Mice were exposed to 2,5-hexanediol at a 1/5 LD50 dose level for 7 days. Pathotoxicological changes

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