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Merck

D7631

Sigma-Aldrich

5,5-二甲基噁唑烷-2,4-二酮

别名:

DMO, NSC 30152, 二甲双酮

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About This Item

经验公式(希尔记法):
C5H7NO3
CAS号:
分子量:
129.11
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

形狀

powder

品質等級

mp

77-80 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

CC1(C)OC(=O)NC1=O

InChI

1S/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8)

InChI 密鑰

JYJFNDQBESEHJQ-UHFFFAOYSA-N

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應用

作为反应物,参与以下反应:
  • 苯并环镍或萘环镍β氧杂氮杂氯配合物的合成
  • 用作组织蛋白酶K抑制剂

参与药理学研究的分子包括:
  • 抗癫痫药生物等效仿制药的鉴定
  • 筛选将能量代谢从线粒体呼吸转变为糖酵解的药物
  • 溶解总胆管囊肿/胰胆管连接不良患者的蛋白塞

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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O M Ocon et al.
Journal of dairy science, 86(4), 1194-1200 (2003-05-14)
Feeding cattle diets high in degradable crude protein (CP) or in excess of requirements can reduce fertility and lower uterine pH. Objectives were to determine direct effects of urea and acidic pH during oocyte maturation and embryonic development. For experiment
Catharina Busch et al.
Acta ophthalmologica, 98(7), e801-e806 (2020-03-03)
To investigate clinical baseline characteristics and optical coherence tomography biomarkers predicting visual loss during observation in eyes with diabetic macular oedema (DMO) and good baseline visual acuity (VA). A sub-analysis of a 12-month, retrospective study, including patients with baseline VA
Deirdre L Zander-Fox et al.
Reproductive biomedicine online, 21(2), 219-229 (2010-07-10)
The preimplantation embryo is highly susceptible to in-vitro stress, and although this does not necessarily perturb blastocyst development, it can significantly affect embryo physiology and the ability to form a viable pregnancy. This study determined that the preimplantation mouse embryo
Matias Iglicki et al.
The British journal of ophthalmology, 104(5), 666-671 (2019-08-09)
We aimed to investigate a novel optical coherence tomography (OCT) finding of outer retinal hyperreflective deposits (ORYDs) in patients with naïve diabetic macular oedema (DMO) seen after small gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling. Furthermore
Sanjeeb Bhandari et al.
Clinical & experimental ophthalmology, 48(4), 462-469 (2019-12-31)
There are limited data on real-world outcomes of cataract surgery in eyes receiving intravitreal treatments for diabetic macular oedema (DMO). Cataract surgery may exacerbate oedema in some eyes with DMO resulting in inferior outcomes. Matched, case-controlled retrospective study of observational

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