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Merck

A79922

Sigma-Aldrich

4-四氢吖啶 盐酸盐 水合物

≥99%

别名:

THA 盐酸盐 水合物, Tacrine hydrochloride, 单满吖啶氨 盐酸盐 水合物

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About This Item

经验公式(希尔记法):
C13H14N2 · HCl · xH2O
分子量:
234.72 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

≥99%

表单

solid

mp

284-286 °C (lit.)

SMILES字符串

O.Cl.Nc1c2CCCCc2nc3ccccc13

InChI

1S/C13H14N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H;1H2

InChI key

PXGRMZYJAOQPNZ-UHFFFAOYSA-N

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应用

9-氨基-1,2,3,4-四氢吖啶盐酸盐水合物是一种众所周知的胆碱酯酶抑制剂,常用于药理学研究。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

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European Journal of Pharmacology, 676(1-3), 64-70 (2012)
Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro.
Ogura H, et al.
Methods and Findings in Experimental and Clinical Pharmacology, 22(8), 609-614 (2000)
A review on cholinesterase inhibitors for Alzheimer?s disease.
Anand P and Singh B
Archives of Pharmacal Research, 36(4), 375-399 (2013)
New Tacrines as Anti-Alzheimer's Disease Agents. The (Benzo) Chromeno-PyranoTacrines.
Oset-Gasque MJ and Marco-Contelles J
Current Topics in Medicinal Chemistry, 17(31), 3349-3360 (2017)

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