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Merck

939692

Sigma-Aldrich

Poly(glycerol sebacate) methacrylate

new

degree of methacrylation 20%, contains 150 ppm MEHQ as inhibitor

别名:

PGS-MA

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About This Item

线性分子式:
[CH2CH(O2C4H5)CH2OOC(CH2)8COO]n
分類程式碼代碼:
12352201

品質等級

形狀

(liquid/paste)

包含

150 ppm MEHQ as inhibitor

顏色

white/yellow

儲存溫度

−20°C

一般說明

Poly(glycerol sebacate) methacrylate (PGS-MA) is a photopolymerizable biodegradable elastomer with tunable mechanical properites that can be used for bioprinting, tissue engineering, and regenerative medicine applications including cardiac, nerve, and muscle tissues. PGS is derived from the naturally occuring metabolites glycerol and sebacic acid, which have both been used for FDA approved biomedical applications. The polymer backbone contains ester bonds that can undergo hydrolytic degradation and can also be covalently crosslinked to form a 3D network at higher temperatures under vacuum. The addition of the methacrylate functional groups provides another mechanism of crosslinking via photopolymerization. The PGS-MA can be quickly and efficiently crosslinked under the exposure of UV and visible light in the presence of a photoinitiatior.

應用

  • Soft tissue engineering such as blood vessels, cornea and nerve tissue
  • Orthopedic implants and regenerative medicine application like muscle tissues
  • Nanoparticle formulation and drug delivery systems
  • Flexible wearable or implantable bioelectronic applications

特點和優勢

  • Flexible elastomer with tunable mechanical properties
  • Higher reversible deformation properties
  • Shape memory
  • Bioresorbable polymer

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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访问文档库

Poly(Glycerol Sebacate) in Biomedical Applications?A Review of the Recent Literature
Vogt L, et al
Advanced Healthcare Materials, 10, 2002026-2002026 (2021)
Synthesis, Characterization and 3D Micro-Structuring via 2-Photon Polymerization of Poly(glycerol sebacate)-Methacrylate?An Elastomeric Degradable Polymer
Pashneh-Tala S, et al
Frontiers in physics, 6 (2018)

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