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Merck

900889

Sigma-Aldrich

苯基-2,4,6-三甲基苯甲酰基次膦酸锂

≥95%

别名:

LAP

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About This Item

经验公式(希尔记法):
C16H16LiO3P
CAS号:
分子量:
294.21
分類程式碼代碼:
12352128
NACRES:
NA.23

品質等級

化驗

≥95%

形狀

crystalline powder

顏色

white to off-white

儲存溫度

2-8°C

SMILES 字串

CC1=C(C(P(C2=CC=CC=C2)(O[Li])=O)=O)C(C)=CC(C)=C1

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應用

苯基-2,4,6-三甲基苯甲酰基次膦酸锂(LAP)是一种水溶性、细胞相容的I型光引发剂,可用于水凝胶或其它聚合物材料的聚合。因为其更高的水溶性、在365nm光下的更快的聚合速率、以及在400nm处的吸光度(可实现可见光聚合),该光引发剂优于Irgacure 2959,更适用于生物学应用。改进的聚合动力学使细胞能够在较低的引发剂浓度和较长波长的光下进行封装,这已被证明能够降低引发剂毒性并提高细胞活力。

特點和優勢

  • 水溶性高
  • 生物相容
  • 对可见光敏感

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Tiffany Zhang et al.
Scientific reports, 10(1), 15796-15796 (2020-09-27)
Inspired by the interesting natural antimicrobial properties of honey, biohybrid composite materials containing a low-fouling polymer hydrogel network and an encapsulated antimicrobial peroxide-producing enzyme have been developed. These synergistically combine both passive and active mechanisms for reducing microbial bacterial colonization.
Joshua D McCall et al.
Biomacromolecules, 13(8), 2410-2417 (2012-06-30)
Photoinitiated polymerization remains a robust method for fabrication of hydrogels, as these reactions allow facile spatial and temporal control of gelation and high compatibility for encapsulation of cells and biologics. The chain-growth reaction of macromolecular monomers, such as acrylated PEG
Zhiguang Qiao et al.
Biomaterials, 266, 120385-120385 (2020-10-30)
Despite significant advances in osteochondral tissue engineering, it remains challenging to successfully reconstruct native-like complex tissues organized in three-dimension with spatially varying compositional, structural and functional properties. In this contribution, inspired by the gradients in extracellular matrix (ECM) composition and
Kavin Kowsari et al.
iScience, 24(11), 103372-103372 (2021-11-27)
To address current unmet needs in terms of scalability and material biocompatibility for future photocrosslinking-based additive manufacturing technologies, emergent platform designs are in inexorable demand. In particular, a shift from the present use of cell-damaging UV light sources in light-based
Andrew C Daly et al.
Nature communications, 12(1), 753-753 (2021-02-04)
Cellular models are needed to study human development and disease in vitro, and to screen drugs for toxicity and efficacy. Current approaches are limited in the engineering of functional tissue models with requisite cell densities and heterogeneity to appropriately model

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