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Merck

541397

Sigma-Aldrich

10-溴癸酸

95%

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About This Item

线性分子式:
Br(CH2)9CO2H
CAS号:
分子量:
251.16
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

95%

反應適用性

reagent type: linker

mp

38-41 °C (lit.)

官能基

bromo
carboxylic acid

SMILES 字串

OC(CCCCCCCCCBr)=O

InChI

1S/C10H19BrO2/c11-9-7-5-3-1-2-4-6-8-10(12)13/h1-9H2,(H,12,13)

InChI 密鑰

PGVRSPIEZYGOAD-UHFFFAOYSA-N

一般說明

10-Bromodecanoic acid can be prepared from 10-bromodecanol via oxidation.

應用

10-Bromodecanoic acid may be employed as an alkylcarboxylate chain source in the preparation of alkylcarboxylate-grafted polyethylenimine. It may also be used in the synthesis of :
  • 10-(methylsulfinyl)decanoic acid
  • 10-cyanodecanoic acid
  • (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)-decyl)triphenylphosphonium bromide
  • 11-thiastearic acid

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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M D Rahman et al.
Journal of medicinal chemistry, 31(8), 1656-1659 (1988-08-01)
A variety of analogues of stearic acid in which one of the methylene groups was replaced by a sulfur atom were examined as inhibitors of growth and fatty acid biosynthesis in the trypanosomatid protozoan Crithidia fasciculata. The 8-, 9-, 10-
Fatemeh Soltani et al.
Artificial cells, nanomedicine, and biotechnology, 45(7), 1356-1362 (2016-11-01)
Poor water solubility of hydrophobic drugs is one of the major problems in pharmaceutical sciences. Herein, in order to address the poor solubility of crocetin, the 30% of primary amines of PAMAM G4 and PPI G4 were alkylated and evaluated
Reza K Oskuee et al.
The journal of gene medicine, 11(10), 921-932 (2009-07-28)
Various strategies have been examined to improve both transfection efficiency and cytotoxicity of polyethylenimine (PEI), a widely used polycationic nonviral gene vector. In the present study, we sought to improve PEI transfection efficiency by combining the osmotic burst mechanism for
Sara Ayatollahi et al.
The international journal of biochemistry & cell biology, 92, 210-217 (2017-10-17)
RNAi-based gene therapy has been recently considered as a promising approach against cancer. Targeted delivery of drug, gene or therapeutic RNAi-based systems to tumor cells is one of the important issues in order to reduce side effects on normal cells.
The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor,(10-oxo-10-(4-(3-thioxo-3 h-1, 2-dithiol-5-yl) phenoxy) decyl) triphenylphosphonium bromide (Ap39).
Le Trionnaire S, et al.
MedChemComm, 5(6), 728-736 (2014)

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