460524

(S)-(-)-4-氯-3-羟基丁酸乙酯

96%

• 线性分子式: ClCH₂CH(OH)CH₂CO₂C₂H₅
• CAS号: 86728-85-0
• 分子量: 166.60
• Beilstein: 4657170
• MDL號碼: MFCD00211241
• 分類程式碼代碼: 12352101
• PubChem物質ID: 24869707
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: 96%
• 光學活性: [α]23/D −14°, neat
• 光學純度: ee: 97% (GLC)
• 折射率: n20/D 1.453 (lit.)
• bp: 93-95 °C/5 mmHg (lit.)
• 密度: 1.19 g/mL at 25 °C (lit.)
• 官能基: chloro; ester; hydroxyl
• SMILES 字串: CCOC(=O)C[C@H](O)CCl
• InChI: 1S/C6H11ClO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3/t5-/m0/s1
• InChI 密鑰: ZAJNMXDBJKCCAT-YFKPBYRVSA-N

说明

一般說明

Ethyl (S)-4-chloro-3-hydroxybutanoate is a chiral intermediate generally used to prepare atorvastatin, a cholesterol-lowering drug.

應用

Ethyl (S)-(−)-4-chloro-3-hydroxybutyrate can be used as a starting material in the synthesis of 4-amino-3-hydroxybutyric acid, a compound of pharmacological importance.

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H318
• 防範說明: P280 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 235.4 °F - closed cup
• 閃點（°C）: 113 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter