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Merck

15450

Sigma-Aldrich

N,N′-二甲基脲

(sym.), ≥99% (from N)

别名:

DMU, 1,3-二甲基脲

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About This Item

线性分子式:
(CH3NH)2CO
CAS号:
分子量:
88.11
Beilstein:
1740672
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥99% (from N)

形狀

solid

反應適用性

reagent type: ligand
reaction type: C-H Activation

bp

268-270 °C (lit.)

mp

101-104 °C (lit.)
103-107 °C

SMILES 字串

CNC(=O)NC

InChI

1S/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)

InChI 密鑰

MGJKQDOBUOMPEZ-UHFFFAOYSA-N

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應用

N,N′-二甲基脲可用于:
  • 作为合成N,N′-二甲基-6-氨基尿嘧啶的起始原料。
  • 与β-环糊精衍生物结合形成低熔点混合物(LMM),用作加氢甲酰化和Tsuji-Trost反应的溶剂。
  • 在无溶剂条件下通过Biginelli缩合合成N,N′-二取代-4-芳基-3,4-二氢嘧啶酮。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

314.6 °F - closed cup

閃點(°C)

157 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Reactions of 1, 3-Dimethyl-5, 6-diaminouracil.
Blicke F F and Godt Jr H C
Journal of the American Chemical Society, 76(10), 2798-2800 (1954)
Low melting mixtures based on β-cyclodextrin derivatives and N, N′-dimethylurea as solvents for sustainable catalytic processes.
Jerome F, et al.
Green Chemistry, 16(8), 3876-3880 (2014)
Hyun-Woong Cho et al.
PloS one, 14(6), e0217745-e0217745 (2019-06-21)
The aim of this study was to investigate the short-term efficacy and safety of Poly-gamma-glutamic acid (γ-PGA) and the immunologic changes in patients with CIN 1. Participants were randomly assigned to one of two groups and orally treated with placebo
Dowex-promoted general synthesis of N, N'-disubstituted-4-aryl-3, 4-dihydropyrimidinones using a solvent-free Biginelli condensation protocol.
Singh K, et al.
Tetrahedron Letters, 47(25), 4205-4207 (2006)
D Collins et al.
American journal of physiology. Gastrointestinal and liver physiology, 298(3), G345-G351 (2009-11-21)
Facilitative UT-B urea transporters enable the passage of urea across cell membranes. Gastrointestinal urea transporters are thought to play a significant role in the urea nitrogen salvaging process that occurs between mammalian hosts and their gut bacteria. This study investigated

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