T3126

D-α-Tocopherol succinate

semisynthetic, 1210 IU/g

• Synonym(s): Vitamin E succinate
• Empirical Formula (Hill Notation): C₃₃H₅₄O₅
• CAS Number: 4345-03-3
• Molecular Weight: 530.78
• Beilstein: 4038233
• EC Number: 224-403-8
• MDL number: MFCD00072055
• UNSPSC Code: 12352205
• eCl@ss: 34058016
• PubChem Substance ID: 24900107
• NACRES: NA.28

Properties

• biological source: semisynthetic
• form: powder
• specific activity: 1210 IU/g
• color: white to yellow
• storage temp.: room temp
• SMILES string: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1
• InChI: 1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1
• InChI key: IELOKBJPULMYRW-NJQVLOCASA-N

Description

General description

α-Tocopherol succinate is a fat soluble vitamin. α-Tocopherol is a form of vitamin E, which can be obtained through dietary sources. RRR-α-tocopherol is a natural form of α-Tocopherol.

Application

D-α-Tocopherol succinate has been used:

• to as a dietary supplement to study its immunomodulatory effects in chicks
• as a dietary supplement in pregnant women to evaluate its effects on arsenic exposure
• as an antioxidant to investigate concurrent pathways of cell death due to acute exercise

Biochem/physiol Actions

α-Tocopherol is also called as a radical-chain breaker due to its anti-oxidant property.

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol succinate is used along the α-Tocopherol acetate, α-Tocopherol nicotinate and other esterified forms as a vitamin E supplement with similar but differential activities.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves