SML2090

NAMI-A

≥98% ruthenium (Ru) basis (elemental analysis)

• Synonym(s): 1H-Imidazole (OC-6-11)-tetrachloro(1H-imidazole-κN3)[1,1′-(sulfinyl-κS)bis[methane]]ruthenate(1-) (1:1), ImH[trans-RuCl4(DMSO)Im], Imidazolium trans-imidazoledimethyl sulfoxide-tetrachlororuthenate
• Empirical Formula (Hill Notation): C₅H₁₀Cl₄N₂ORuS · C₃H₅N₂
• CAS Number: 201653-76-1
• Molecular Weight: 458.18
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥98% ruthenium (Ru) basis (elemental analysis)
• form: powder
• storage condition: desiccated
• color: faint red to dark brown
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: CS(C)=O.Cl[Ru](Cl)(Cl)Cl.N1=CNC=C1.C2=[NH+]C=CN2
• InChI key: HIAWXYSWERGOAJ-UHFFFAOYSA-K

Description

Biochem/physiol Actions

NAMI-A is a potent antimetastatic drug in vivo that is exhibits little cytotoxicity towards many cancer cell lines. Antimetastatic of NAMI-A is attributed to the formation of adducts with membrane and cytosolic proteins. Nevertheless NAMI-A induces potent and selective cytotoxic effects in several leukemia cell lines. NAMI-A exhibits low toxicity for host tissues.

NAMI-A is a ruthenium-based anticancer agent.

potent antimetastatic drug

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable