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K8250

Sigma-Aldrich

11-Ketotestosterone

Synonym(s):

17β-Hydroxy-4-androstene-3,11-dione, 17β-Hydroxyandrost-4-ene-3,11-dione, 4-Androsten-17β-ol-3,11-dione

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About This Item

Empirical Formula (Hill Notation):
C19H26O3
CAS Number:
564-35-2
Molecular Weight:
302.41
MDL number:
MFCD00198520
UNSPSC Code:
12352202
PubChem Substance ID:
24896245
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

Assay

≥98.00% (TLC)

form

powder

drug control

Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

ethanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

InChI

1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-14,16-17,22H,3-8,10H2,1-2H3/t13-,14-,16-,17+,18-,19-/m0/s1

InChI key

WTPMRQZHJLJSBO-XQALERBDSA-N

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Biochem/physiol Actions

11-Ketotestosterone is a minor androgen in humans, but a major androgen in fish.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K O Skaftnesmo et al.
BMC genomics, 18(1), 801-801 (2017-10-20)
Our understanding of the molecular mechanisms implementing pubertal maturation of the testis in vertebrates is incomplete. This topic is relevant in Atlantic salmon aquaculture, since precocious male puberty negatively impacts animal welfare and growth. We hypothesize that certain miRNAs modulate
April Feswick et al.
Environmental toxicology and chemistry, 33(4), 847-857 (2014-01-01)
Endocrine-disrupting chemicals are exogenous substances that can impact the reproduction of fish, potentially by altering circulating concentrations of 17β-estradiol (E2), testosterone (T), and 11-ketotestosterone (11-KT). Common methods to measure steroids in plasma samples include radioimmunoassays (RIAs) and enzyme-linked immunosorbant assays
Hankun Li et al.
Scientific reports, 9(1), 10645-10645 (2019-07-25)
Hepatocellular carcinoma (HCC) is one of the most severe cancer types and many genetic and environmental factors contribute to the development of HCC. Androgen receptor (AR) signaling is increasingly recognized as one of the important factors associated with HCC. Previously
Ryusuke Sudo et al.
Zoological science, 29(4), 254-259 (2012-04-04)
To evaluate the effects of sex steroids on silvering in the Japanese eel, Anguilla japonica, the development of oocytes, eye size, digestive tract, and swim bladder were studied in relation to observations of the profiles of plasma levels of sex
Felipe Alonso et al.
Physiology & behavior, 106(5), 612-618 (2012-04-24)
In this work we characterized the social hierarchy of non-reproductive individuals of Cichlasoma dimerus (Heckel, 1840), independently for both sexes, and its relationship to the opportunity for social status ascent. Female and male individuals who were located on the top
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