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DMPS5X

Sigma-Aldrich

Dimethylpolysiloxane

viscosity 50 cSt (25 °C)(lit.)

Synonym(s):

Polydimethylsiloxane

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.25

form

liquid

Quality Level

mol wt

~3,780

viscosity

50 cSt(25 °C)(lit.)

InChI

1S/C2H6OSi/c1-4(2)3/h1-2H3

InChI key

SEUDSDUUJXTXSV-UHFFFAOYSA-N

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Application

Dimethylpolysiloxane has been used:
  • in culturing mouse embryos
  • in preparation of oil-based nano-adjuvant candidates
  • to reduce the brain movement in the post-cat craniotomy process

Clear, colorless fluid polymer useful as a stationary phase in gas chromatography and as an anti-foaming agent.

Biochem/physiol Actions

Dimethylpolysiloxane is a silicon-based organic polymer, inert and non-toxic. It is applicable in the pharmaceutical, food, and cosmetic industry. Dimethylpolysiloxane is excreted unchanged unaltered in the faeces and is non-mutagenic.
Dimethylpolysiloxane is used in protein chromatography and affininty chromatography. Dimethylpolysiloxane was used to determine that postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

609.8 °F - closed cup

Flash Point(C)

321 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zengguang Ma et al.
Neuroscience letters, 637, 161-167 (2016-11-20)
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Sun, et al.
Brain Stimulation, 11, 667-675 (2019)
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Vaccines, 9(3) (2021-04-04)
Many conventional vaccines are administered via a needle injection, while most pathogens primarily invade the host via mucosal surfaces. Moreover, protective IgA antibodies are insufficiently induced by parenteral vaccines. Mucosal immunity induces both local and systemic response to pathogens and
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Investigative ophthalmology & visual science, 61(5), 59-59 (2020-05-29)
To physiologically examine the impairment of cortical sensitivity to visual motion during acute elevation of intraocular pressure (IOP). Motion processing in the cat brain is well characterized, its X and Y cell visual pathways being functionally analogous to parvocellular and
Negin P Martin et al.
Journal of visualized experiments : JoVE, (141) (2018-11-20)
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