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45690

Sigma-Aldrich

Erythrosin extra bluish

for microscopy (Bact., Hist.), adsorption and fluorescent indicator

Synonym(s):

2′,4′,5′,7′-Tetraiodofluorescein disodium salt, Acid Red 51, Iodoeosin

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About This Item

Empirical Formula (Hill Notation):
C20H6I4Na2O5
CAS Number:
16423-68-0
Molecular Weight:
879.86
Colour Index Number:
45430
Beilstein:
1443945
EC Number:
240-474-8
MDL number:
MFCD00144257
UNSPSC Code:
12171500
PubChem Substance ID:
329756903
NACRES:
NA.47

grade

adsorption and fluorescent indicator
for microscopy (Bact., Hist.)

form

solid

technique(s)

titration: suitable

SMILES string

[Na+].[Na+].[O-]c1c(I)cc2c(Oc3c(I)c([O-])c(I)cc3C24OC(=O)c5ccccc45)c1I

InChI

1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2

InChI key

RAGZEDHHTPQLAI-UHFFFAOYSA-L

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General description

Erythrosin extra bluish is a brown color powder, that is soluble in ethanol and water. Its pH ranges from 2.5 to 4. It is used in color filters, light emitting diodes, cosmetics, hair dyes etc. It has several biological applications like detecting gene expression, treating age related macular degeneration, diabetes, obesity etc.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302 - H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3447-3451 (2012-08-01)
Erythrosine (ErB) is a xanthene and an US Food and Drug Administration approved dye used in foods, drugs and cosmetics. Although its utilization is permitted, ErB is described as inhibitor of enzymes and protein-protein interactions and is toxic to pituitary
Vagner Roberto Batistela et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 889-897 (2011-05-10)
Xanthenes form to an important class of dyes which are widely used. Most of them present three acid-base groups: two phenolic sites and one carboxylic site. Therefore, the pKa determination and the attribution of each group to the corresponding pKa
Laura Carmen Apostol et al.
Biodegradation, 23(5), 725-737 (2012-03-23)
Biodegradation of a xanthene dyes was investigated for the first time using anaerobic granular sludge. On a first screening, biomass was able to decolorize, at different extents, six azo dye solutions: acid orange 7, direct black 19, direct blue 71
Chueh-Pin Chen et al.
Photochemistry and photobiology, 88(3), 570-576 (2012-01-31)
The growing resistance to antibiotics has rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers and was therefore used in this study to investigate
Wei Zhang et al.
Journal of the American Chemical Society, 133(51), 20680-20683 (2011-12-03)
We report the use of a simple complex assembled from Ni(II) salt and 2-mecaptoethanol in one step in water as the efficient catalyst in a molecular hydrogen system which can be sensitized by a low-cost xanthene dye, Erythrosin B. An
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