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320617

Sigma-Aldrich

Ethyl 4-hydroxy-3-methoxycinnamate

98%

Synonym(s):

Ethyl ferulate

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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2C2H5
CAS Number:
4046-02-0
Molecular Weight:
222.24
EC Number:
223-745-5
MDL number:
MFCD00009190
UNSPSC Code:
12352100
PubChem Substance ID:
24859274
NACRES:
NA.22

Assay

98%

form

solid

bp

164-166 °C/0.5 mmHg (lit.)

mp

63-65 °C (lit.)

functional group

ester

SMILES string

CCOC(=O)\C=C\c1ccc(O)c(OC)c1

InChI

1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+

InChI key

ATJVZXXHKSYELS-FNORWQNLSA-N

Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000319332
MKCS1397
0000319332
MKCV1750
MKCN3305

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K J Rashamuse et al.
Journal of applied microbiology, 103(5), 1610-1620 (2007-10-24)
Isolation and identification of bacterial isolates with specific ferulic acid (FA) esterase activity and cloning of a gene encoding activity. A micro-organism with ethyl ferulate hydrolysing (EFH) activity was isolated by culture enrichment techniques. Detailed molecular identification based on species-specific
T Nakayama et al.
Bioscience, biotechnology, and biochemistry, 60(2), 316-318 (1996-02-01)
Cytotoxicity and DNA single-strand breaks caused by H2O2 were assessed by a colony formation assay and a DNA precipitation assay, respectively, with Chinese hamster V79 cells. In both assays, caffeic acid ethyl ester showed protective effects. The structure-activity relationship showed
Gururaj Joshi et al.
Neurochemistry international, 48(4), 318-327 (2006-01-03)
Ferulic acid ethyl ester (FAEE) is an ester derivative of ferulic acid, the latter known for its anti-inflammatory and antioxidant properties. Previous studies from our laboratory have shown that ferulic acid protects synaptosomal membrane system and neuronal cell culture systems
Mirko Bunzel et al.
Journal of agricultural and food chemistry, 56(21), 10368-10375 (2008-10-10)
Valuable information about possible types of linkages, reaction mechanisms, and sequences for oxidative coupling of phenolic compounds in planta is available from in vitro model systems. Ferulate oligomers were generated in a system using ethyl ferulate, peroxidase, and hydrogen peroxide
Yun Feng et al.
Biochimica et biophysica acta, 1780(4), 659-672 (2008-01-31)
It is an important therapeutic strategy to protect mitochondria from oxidative stress, especially during ischemia-reperfusion. In the present study, an attempt has been made to evaluate the protective effects of caffeic acid phenethyl ester (CAPE) and its related phenolic compounds
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