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SAB5600204

Sigma-Aldrich

Anti-beta-Actin antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM112, purified immunoglobulin

Synonym(s):

ACTB, Actin cytoplastic 1, actin beta, beta-actin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

recombinant

expressed in HEK 293 cells

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM112, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

all

technique(s)

ChIP: 1:200
ELISA: suitable (assay dependent concentration)
flow cytometry: suitable (assay dependent concentration)
immunocytochemistry: 1:200
immunohistochemistry: 1:200
immunoprecipitation (IP): 1:200
western blot: 1:1000

isotype

IgG

NCBI accession no.

60

UniProt accession no.

P60709

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ACTB(60)

Related Categories

Specificity

This antibody reacts to beta-Actin (Actin, cytoplasmic 1). No cross reactivity with other isoforms of Actin.

Immunogen

A peptide corresponding to the N-terminus of beta-actin

Physical form

Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vipul K Singh et al.
Journal of controlled release : official journal of the Controlled Release Society, 349, 796-811 (2022-08-02)
We describe a role of CD44-mediated signaling during host-defense against tuberculosis (TB) using a mouse model of TB and studies in M. tuberculosis (Mtb) infected human macrophage (MФ). Liposomes targeting CD44 using thioaptamers (CD44TA-LIP) were designed and tested as new
Abhishek Mishra et al.
Frontiers in immunology, 13, 859116-859116 (2022-06-01)
GM-CSF is an important cytokine that regulates the proliferation of monocytes/macrophages and its various functions during health and disease. Although growing evidences support the notion that GM-CSF could play a major role in immunity against tuberculosis (TB) infection, the mechanism
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Clinical epigenetics, 16(1), 10-10 (2024-01-10)
Metastasis is the primary cause of recurrence and death in patients with papillary thyroid carcinoma (PTC). LncRNA ACTA2-AS1, a long non-coding RNA, acts as a tumor suppressor in multiple types of human malignancies, while the role of ACTA2-AS1 in PTC
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Arthritis & rheumatology (Hoboken, N.J.), 74(4), 654-664 (2021-11-09)
Salivary gland epithelial cells (SGECs) are key cellular drivers in the pathogenesis of primary Sjögren's syndrome (SS); however, the mechanisms sustaining SGEC activation in primary SS remain unclear. We undertook this study to determine the role of autophagy in the
Chung-Chih Tseng et al.
Scientific reports, 12(1), 10513-10513 (2022-06-23)
Oral squamous cell carcinoma (OSCC) is a common malignant tumor worldwide that is characterized by abnormal lesions or malignant hyperplasia of soft and hard tissues in the oral cavity. Previous research has found that HDAC6 may be a potential therapeutic
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