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33973

Supelco

Clorsulon

VETRANAL®, analytical standard

Synonym(s):

4-Amino-6-(trichlorovinyl)-1,3-benzenedisulfonamide

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About This Item

Empirical Formula (Hill Notation):
C8H8Cl3N3O4S2
CAS Number:
60200-06-8
Molecular Weight:
380.66
EC Number:
262-100-2
MDL number:
MFCD00072006
UNSPSC Code:
41116107
PubChem Substance ID:
329754714
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Nc1cc(\C(Cl)=C(\Cl)Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI

1S/C8H8Cl3N3O4S2/c9-7(8(10)11)3-1-4(12)6(20(14,17)18)2-5(3)19(13,15)16/h1-2H,12H2,(H2,13,15,16)(H2,14,17,18)

InChI key

QOVTVIYTBRHADL-UHFFFAOYSA-N

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General description

Clorsulon, is a benzene sulphonamide and a flukicide, which is found to be effective against the adult and immature form of liver fluke, Fasciola hepatica in cattle.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8206
BCBV4517
SZBE090XV
SZBB102XV
SZE9140X

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A F Loyacano et al.
Journal of the American Veterinary Medical Association, 218(9), 1465-1468 (2001-05-10)
To compare effects of an injectable doramectin preparation with those of an injectable ivermectin-clorsulon preparation on control of gastrointestinal nematodes and liver flukes and on growth performance in cattle. Randomized complete block design. 60 crossbred calves. Calves (20/treatment group) were
M Meaney et al.
Parasitology research, 91(3), 238-250 (2003-08-26)
The ultrastructural changes in Fasciola hepatica induced by the fasciolicide clorsulon were assessed using scanning electron microscopy. At 8 and 44 weeks post-infection, male Sprague-Dawley rats infected with F. hepaticawere dosed orally with clorsulon at a concentration of 12.5 mg/kg
M Meaney et al.
Parasitology research, 95(2), 117-128 (2004-12-14)
Three experiments were carried out in vitro to determine the roles of the tegument and gut of Fasciola hepatica in the uptake of the flukicidal drug, clorsulon. Changes to the two surfaces were assessed by scanning electron microscopy. In the
T A Morsy et al.
Journal of the Egyptian Society of Parasitology, 31(1), 79-85 (2003-02-01)
Scabies infestation is a community health problem worldwide. This is particularly true in overcrowded and unhygienic areas. Seven dogs were experimentally infested with Sarcoptes scabiei freshly recovered from a patient. The dogs after infestation were treated with a mixture of
L Moll et al.
Veterinary parasitology, 91(1-2), 153-158 (2000-07-13)
In the winter of 1998/1999, sheep on a farm in the province of North Holland, The Netherlands, died from subacute and chronic liver fluke disease despite four previous treatments with triclabendazole (TCBZ). Faecal examinations of sheep and cattle on the
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