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791108C

Avanti

18:2 Cardiolipin-d5

Avanti Research™ - A Croda Brand

Synonym(s):

1′,3′-bis[1,2-dilinoleoyl-sn-glycero-3-phospho]-glycerol-d5 (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C81H143D5N2O17P2
CAS Number:
2315262-46-3
Molecular Weight:
1489.02
UNSPSC Code:
51191904
NACRES:
NA.28
Assay:
99% (TLC)
Form:
solution
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assay

99% (TLC)

form

solution

packaging

package of 1 × 1 mg (791108C-1MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL in chloroform

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P([O-])(OC[C@@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)OC([2H])([2H])C([2H])(O)C([2H])([2H])OP([O-])(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[NH4+].[NH4+]

InChI key

MKKYVXUKKDNVFX-VQISHCRGSA-N

General description

18:2 Cardiolipin-d5 is a deuterated derivative of 18:2 Cardiolipin-d5. Cardiolipin is a prevalent di-phospholipid found in mammals. It is synthesized in the inner leaflet of the inner mitochondrial membrane.

Biochem/physiol Actions

Cardiolipin plays an important role in oxidative phosphorylation. It is also involved in regulating mitochondria-induced apoptosis. Cardiolipin binds to mitochondrial proteins, which are involved in adenosine triphosphate (ATP) production. It also binds to peroxidase and interacts with cytochrome C, respectively.

Packaging

5 mL Clear Glass Sealed Ampule (791108-1MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Dietary docosahexaenoic acid (22: 6) incorporates into cardiolipin at the expense of linoleic acid (18: 2): analysis and potential implications
Cortie C H and Else P L
International Journal of Molecular Sciences, 13(11), 15447-15463 (2012)