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I3875

Sigma-Aldrich

Indoxyl sulfate potassium salt

Synonym(s):

Potassium 3-indoxyl sulfate, Urinary indican

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About This Item

Linear Formula:
C8H6NO4SK
CAS Number:
Molecular Weight:
251.30
Beilstein:
3921324
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

> 98 %

Quality Level

mp

165 °C (dec.) (lit.)

solubility

water: soluble

storage temp.

−20°C

SMILES string

[K+].[O-]S(=O)(=O)Oc1c[nH]c2ccccc12

InChI

1S/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1

InChI key

MDAWATNFDJIBBD-UHFFFAOYSA-M

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General description

Indoxyl sulfate potassium salt is derived from indoxyl sulfate by replacing the hydrogen ion with a potassium cation. Potassium indoxyl sulfate is used as a reagent for the detection and determination of hydrogen peroxide.

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Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hidehisa Shimizu et al.
Life sciences, 92(2), 143-148 (2012-12-04)
Intercellular adhesion molecule 1 (ICAM-1) plays an important role in adhesion of monocytes/macrophages to injured tubulointerstitial tissue. The present study aimed to determine if indoxyl sulfate, a uremic toxin, regulates renal expression of ICAM-1. The effect of indoxyl sulfate on
Tino Vollmer et al.
Scientific reports, 9(1), 14525-14525 (2019-10-12)
Identifying the key toxic players within an in-vivo toxic syndrome is crucial to develop targeted therapies. Here, we established a novel method that characterizes the effect of single substances by means of an ex-vivo incubation set-up. We found that primary
Suree Lekawanvijit et al.
Circulation research, 111(11), 1470-1483 (2012-11-10)
Cardiorenal syndrome is a condition in which a complex interrelationship between cardiac dysfunction and renal dysfunction exists. Despite advances in treatment of both cardiovascular and kidney disease, cardiorenal syndrome remains a major global health problem. Characteristic of the pathophysiology of
Carel J Pretorius et al.
Clinica chimica acta; international journal of clinical chemistry, 419, 122-126 (2013-02-23)
The uremic toxins indoxyl sulphate (IS) and p-cresyl sulphate (pCS) are absorbed bacterial metabolites of tryptophan and tyrosine respectively and may be predictive of clinical outcome. Long chromatography times, incomplete data on the reference ranges of the free and total
Tetsuhiro Tanaka et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(10), 4059-4075 (2013-06-25)
Chronic hypoxia in the tubulointerstitium serves as a final common pathway in progressive renal disease. Circumstantial evidence suggests that hypoxia-inducible factor (HIF)-1 in the ischemic tubules may be functionally inhibited in a chronic kidney disease (CKD) milieu. In this study

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