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C106402

Sigma-Aldrich

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate

95%

Synonym(s):

4-[2-[(Cyclohexylcarbonimidoyl)amino]ethyl]-4-methylmorpholinium p-toluenesulfonate, N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate salt, CMC, CMC metho-p-toluenesulfonate, Morpho CDI

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About This Item

Empirical Formula (Hill Notation):
C14H26N3O · C7H7O3S
CAS Number:
2491-17-0
Molecular Weight:
423.57
EC Number:
219-650-3
MDL number:
MFCD00011979
UNSPSC Code:
12352111
PubChem Substance ID:
329774842
NACRES:
NA.26

Quality Level

200

Assay

95%

form

crystals

mp

113-115 °C (lit.)

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3

InChI

1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

InChI key

GBCAVSYHPPARHX-UHFFFAOYSA-M

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Application

Employed in a facile sequencing technique for pseudouridylate residues in RNA.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBL1691
STBK9581
STBK5448
STBK4239
STBK3756

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A Bakin et al.
Biochemistry, 32(37), 9754-9762 (1993-09-21)
A new technique has been developed for the facile location of pseudouridylate (psi) residues in any RNA molecule. The method uses two known modification procedures which in combination uniquely identify U residues which have been converted into psi. The first
Carola Schafer et al.
Malaria journal, 17(1), 370-370 (2018-10-20)
Plasmodium vivax is the most geographically widespread of the human malaria parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites have the unique feature of forming dormant liver stages (hypnozoites) that can reactivate weeks or months after a parasite-infected
W A Ziehler et al.
Current protocols in nucleic acid chemistry, Chapter 6, Unit 6-Unit 6 (2008-04-23)
This unit provides thorough coverage of the most useful chemical and enzyme probes that can be used to examine RNA secondary and tertiary structure. Footprinting methods are presented using dimethyl sulfate, diethyl pyrocarbonate, ethylnitrosourea, kethoxal, CMCT, and nucleases. For chemical
S Garlapati et al.
Journal of molecular biology, 308(4), 623-638 (2001-05-15)
Enhanced translation of giardiavirus (GLV)-luciferase chimeric mRNA in Giardia lamblia requires the presence of the initial 264 nucleotides of the viral capsid-coding region. A 13 nt downstream box (DB) sequence within this region, complementary to a 15 nt sequence near
Jinghui Song et al.
Nature chemical biology, 16(2), 160-169 (2019-12-11)
Pseudouridine synthases (PUSs) are responsible for installation of pseudouridine (Ψ) modification in RNA. However, the activity and function of the PUS enzymes remain largely unexplored. Here we focus on human PUS10 and find that it co-expresses with the microprocessor (DROSHA-DGCR8
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