A56655
4-Amino-3-hydroxybutyric acid
98%
Synonym(s):
DL-γ-Amino-β-hydroxybutyric acid
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About This Item
Linear Formula:
H2NCH2CH(OH)CH2CO2H
CAS Number:
Molecular Weight:
119.12
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
powder or crystals
reaction suitability
reaction type: solution phase peptide synthesis
color
white to yellow
mp
223 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
NCC(O)CC(O)=O
InChI
1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)
InChI key
YQGDEPYYFWUPGO-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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[Neurochemical aspects of the pharmacology of GABAergic substances].
K S Raevskiĭ
Farmakologiia i toksikologiia, 44(5), 517-529 (1981-09-01)
T Noto et al.
Journal of neurochemistry, 51(2), 548-551 (1988-08-01)
gamma-Amino-beta-[3H]hydroxybutyric acid ([3H]-GABOB) was formed in rat brain from 2-[3H]-hydroxyputrescine that had been chemically synthesized from 2-oxoputrescine and [3H]sodium borohydride. After the injection of 2-[3H]hydroxyputrescine into the lateral ventricle of a rat brain, the rat was killed and then the
gamma-Amino-beta-hydroxybutyric acid as add-on therapy in adult patients with severe focal epilepsy.
E García-Flores et al.
Stereotactic and functional neurosurgery, 69(1-4 Pt 2), 243-246 (1997-01-01)
Total seizure frequency was evaluated among adult patients with severe partial epilepsy refractory to medical treatment. Clinical status was assessed before, and after a synthetic analog of gamma-amino-beta-hydroxybutyric acid (GABOB) was used as add-on therapy. Twenty-five patients with temporal and
R Chemello et al.
Rivista di neurologia, 50(4), 253-268 (1980-07-01)
Effects of GABOB on experimental induced epileptiform activities. Antiepileptic activity of gamma-amino-beta-hydroxybutyric acid (GABOB) has been tested on different models of either generalized or focal epilepsy induced by penicillin in cat. In acute experiments, topical application to the cortex of
Zhenjun Du et al.
Chirality, 16(8), 516-519 (2004-08-04)
Rh(2)(4S-MEOX)(4) and ethereal solvent are the best catalytic system for the enantioselective intramolecular C-H insertion of N-(2-benzyloxyethyl)-N-(tert-butyl)diazoacetamide 2. The highest enantiomeric excess obtained was 91%. A new route for the asymmetric synthesis of gamma-amino-beta-hydroxybutyric acid (GABOB) has been developed.
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