185213

1,1,4,4-Tetraphenyl-1,3-butadiene

suitable for scintillation, ≥99%

• Synonym(s): TPB
• Linear Formula: (C₆H₅)₂C=CHCH=C(C₆H₅)₂
• CAS Number: 1450-63-1
• Molecular Weight: 358.47
• Beilstein: 1914229
• EC Number: 215-914-7
• MDL number: MFCD00004766
• UNSPSC Code: 12352103
• PubChem Substance ID: 24850677
• NACRES: NA.23

Properties

• Assay: ≥99%
• form: solid
• mp: 207-209 °C (lit.)
• suitability: suitable for scintillation
• SMILES string: c1ccc(cc1)\C(=C\C=C(/c2ccccc2)c3ccccc3)c4ccccc4
• InChI: 1S/C28H22/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)21-22-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h1-22H
• InChI key: KLCLIOISYBHYDZ-UHFFFAOYSA-N

Description

Application

• Antihistamine biochemical reagent: Diphenhydramine hydrochloride is widely used as a potent H1 histamine receptor antagonist in biochemical assays to study allergic reactions and antihistamine effects, underscoring its utility in pharmacological research (Quinn et al., 2024).


• In vitro pharmacological studies: This compound serves as a critical tool in in vitro pharmacological studies, particularly for understanding the dynamics of histamine interactions and receptor activity, providing essential insights into allergic response mechanisms (Pitts et al., 2024).


• Diphenhydramine hydrochloride solubility: Its solubility in various solvents makes it an ideal candidate for experiments requiring precise dosages and concentrations in solution form, facilitating its use in liquid pharmaceutical formulations and research applications (Kumar et al., 2023).


• High purity Diphenhydramine HCl for biochemical research: The availability of high-purity diphenhydramine hydrochloride is crucial for conducting accurate and reproducible research, especially in studies related to its pharmacokinetics and pharmacodynamics (Pitts et al., 2024).


• Diphenhydramine HCl aqueous solution for scientific laboratory use: This compound is often prepared in aqueous solutions for experimental use, supporting various scientific studies that require a well-characterized antagonist to explore the pathways and effects of histamine in biological systems (Kumar et al., 2023).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves