T1660
Nε,Nε,Nε-Trimethyllysine hydrochloride
≥97% (TLC)
Synonym(s):
1-Pentanaminium, 5-amino-5-carboxy-N,N,N-trimethyl-, chloride (1:1), (5S)-
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About This Item
Empirical Formula (Hill Notation):
C9H20N2O2 · HCl
CAS Number:
Molecular Weight:
224.73
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
Assay
≥97% (TLC)
form
powder
contains
salts and water as balance
composition
Amino acid content, ~75%
technique(s)
LC/MS: suitable
color
white
storage temp.
−20°C
SMILES string
[Cl-].C[N+](C)(C)CCCC[C@H](N)C(O)=O
InChI
1S/C9H20N2O2.ClH/c1-11(2,3)7-5-4-6-8(10)9(12)13;/h8H,4-7,10H2,1-3H3;1H/t8-;/m0./s1
InChI key
ZKIJKCHCMFGMCM-QRPNPIFTSA-N
Related Categories
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Naomi van Vlies et al.
Analytical biochemistry, 354(1), 132-139 (2006-05-19)
Although the mouse frequently is used to study metabolism and deficiencies therein, little is known about carnitine biosynthesis in this animal. To this point, only laborious procedures have been described to measure the activity of carnitine biosynthesis enzymes using subcellular
Importance of charge independent effects in readout of the trimethyllysine mark by HP1 chromodomain.
Zhenyu Lu et al.
Journal of the American Chemical Society, 131(41), 14928-14931 (2009-10-01)
Histone modifications are implicated in epigenetic inheritance and are of central importance in regulating chromatin structure and gene expression. A prototype example is the trimethylation (Me3) of lysine 9 on histone 3 (H3), which is a readout by an aromatic
Maren Fischer et al.
The British journal of nutrition, 101(2), 190-196 (2008-05-22)
This study was performed to investigate whether dietary lysine concentration influences the carnitine status of pigs. Therefore, an experiment with twenty young pigs with an average body weight of 21 kg was performed which were fed either a control diet
Naomi van Vlies et al.
The FEBS journal, 274(22), 5845-5851 (2007-10-20)
The first enzyme of carnitine biosynthesis is the mitochondrial 6-N-trimethyllysine dioxygenase, which converts 6-N-trimethyllysine to 3-hydroxy-6-N-trimethyllysine. Using progressive membrane solubilization with digitonin and protease protection experiments, we show that this enzyme is localized in the mitochondrial matrix. Latency experiments with
Lei Xiong et al.
Journal of the American Society for Mass Spectrometry, 20(6), 1172-1181 (2009-03-24)
Core histones are susceptible to a range of post-translational modifications (PTMs), including acetylation, phosphorylation, methylation, and ubiquitination, which play important roles in the epigenetic control of gene expression. Here, we observed an unusual discrepancy between MALDI-MS/MS and ESI-MS/MS on the
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