L6420
Luteinizing Hormone from human pituitary
≥8,500 IU/mg
Synonym(s):
ICSH, LH, PLH
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Biochem/physiol Actions
Two-chain glycoprotein hormone; the α-chain is identical to that of chorionic gonadotropin, TSH, and FSH, while biological specificity is attributed to the distinct β-chain. Induces ovulation, spermatogenesis, and synthesis of steroid sex hormones. Activity is mediated through a trans-membrane LH/chorionic gonadotropin receptor that is a member of the G-protein coupled receptor (GPCR) family.
Physical form
Lyophilized from 50 mM ammonium bicarbonate
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Mitsuru Komeya et al.
Scientific reports, 6, 21472-21472 (2016-02-20)
In contrast to cell cultures, particularly to cell lines, tissues or organs removed from the body cannot be maintained for long in any culture conditions. Although it is apparent that in vivo regional homeostasis is facilitated by the microvascular system
Hanyong Jin et al.
Biochemical and biophysical research communications, 482(4), 877-882 (2016-11-29)
Pituitary gonadotropins are key hormones that orchestrate the growth and development of ovarian follicles. However, limited information is available on intra-ovarian factors that mediate the actions of gonadotropins. In this study, we identified that the early growth response 2 gene
Cheng Peng et al.
General and comparative endocrinology, 267, 90-97 (2018-06-19)
Luteinizing hormone receptor (LHR) plays a critical role in reproduction by mediating LH signaling in the gonad. In this study, we cloned a novel lhr gene from the orange-spotted grouper, named glhr2. The cloned complete open reading frame sequence of
Affiefa Yawer et al.
Toxicology and applied pharmacology, 404, 115177-115177 (2020-08-03)
A decline in male fertility possibly caused by environmental contaminants, namely endocrine-disrupting chemicals (EDCs), is a topic of public concern and scientific interest. This study addresses a specific role of testicular gap junctional intercellular communication (GJIC) between adjacent prepubertal Leydig
Xuerui Yao et al.
Theriogenology, 151, 66-73 (2020-04-21)
Zearalenone (ZEA), which is produced by several fusarium mycotoxins, is found in animal feed and food products, and can exert estrogen-like activity. Melatonin (MT) is emerging as a supplement that can fight the toxic effects of mycotoxins. With a variety
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