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C2485

Sigma-Aldrich

β-Cyclodextrin polymer

powder

Synonym(s):

Beta-Cyclodextrin Polymeric Adsorbent

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About This Item

MDL number:
MFCD03456204
UNSPSC Code:
12352201
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

synthetic

Quality Level

100

form

powder

mol wt

average mol wt 2,000-300,000 Da

composition

Cyclodextrin content, 60% iodometric

color

white

solubility

H2O: soluble 100mg plus 1 mL, clear, colorless to light yellow

storage temp.

2-8°C

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General description

Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via α(1,4) glycosidic bonds. Common cyclodextrins contain six (α-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivatized through esterification at positions two, three and/or six.[1]

Application

Beta-cyclodextrin (β-Cyclodextrin) may be used in the development of biocompatible drug delivery vehicles and membrane constructs to improve compound solubility in aqueous environments. β-cyclodextrin polymer and its ester derivatives are used for the development and construction of biomaterials such as hydrogels, nanoassemblies and biomatricies.[2] β-cyclodextrin may be used for the development of biosensors.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ0142
BCCH0282
BCCG5680
BCCD7360
BCCC9890

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Jun Zhao et al.
Journal of chromatography. A, 1216(45), 7840-7845 (2009-10-10)
The expansion and hydrodynamic properties of matrix are significant for expanded bed adsorption (EBA) processes. A series of new composite matrices CroCD-TuC are studied and estimated in an expanded bed. It is found that the heavier matrix is better suited
S Daoud-Mahammed et al.
Journal of biomedical materials research. Part A, 86(3), 736-748 (2007-11-29)
This study aims to investigate the rheological properties of self-assembling gels containing cyclodextrins with potential application as injectable matrix for the sustained delivery of poorly soluble drugs. The ability of these gels to entrap two hydrophobic molecules, benzophenone (BZ) and
Jie Li et al.
Fitoterapia, 93, 163-167 (2014-01-22)
Six 3,3″-biflavanones, including a new compound isochamaejasmenin C (1), were isolated from EtOH extracts of the roots of Stellera chamaejasme L. Their structures were elucidated on the basis of spectroscopic methods, including HR-ESI-MS and 2D NMR techniques. The absolute configurations
Thimma Reddy Thatiparti et al.
Macromolecular bioscience, 10(1), 82-90 (2009-09-10)
Novel beta-cyclodextrin polymer (CD)-based drug delivery hydrogels were prepared by varying type and concentration of crosslinkers and optimizing the gel synthesis conditions. For comparison, dextrose gels were prepared using the same crosslinkers. The optimized gels were characterized by Fourier Transform
Chao Yuan et al.
Food chemistry, 152, 140-145 (2014-01-22)
The inclusion complex of ethyl benzoate with hydroxypropyl-β-cyclodextrin (HPCD) was prepared by a freeze-drying method and its characterizations were investigated by different analytical techniques including UV, FT-IR and phase solubility methods. All these approaches indicated that ethyl benzoate was able
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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Is the shown formula (scheme) of β-Cyclodextrin polymer accurate ? it indicates a macromolecule of precise molecular weight, i.e., 7 repeat units , each is a beta-cyclodextrin. The specification sheet indicates a dispersity in Mw

    1 answer

    1. The structure shown on the product detail page and the specification sheet for this product is a correct representation of the monomer used to make it. The monomer has an active epoxide group. This product is a polymer, with (potentially) a very large distribution of molecular weights. The average molecular weight and the molecular weight distribution could vary from lot-to-lot, but neither is determined on a lot-specific basis.

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