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94261

LL-37 (human) trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

Human LL-37 amide Trifluoroacetate

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About This Item

Empirical Formula (Hill Notation):
C205H341N61O52 · xC2HF3O2
Molecular Weight:
4492.28 (free base basis)
NACRES:
NA.85
UNSPSC Code:
51101500
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Quality Segment

assay

≥95% (HPLC)

form

powder (Lyophilisate)

color

colorless to white

solubility

H2O: 1 mg/mL, clear, colorless

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, viruses

mode of action

cell membrane | interferes

storage temp.

−20°C

General description

Chemical structure: peptide

Application

LL-37 is used to study host defense mechanisms.

Biochem/physiol Actions

LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria.

Packaging

1mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.

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LL-37 (human) trifluoroacetate salt ≥95% (HPLC)

Sigma-Aldrich

94261

LL-37 (human) trifluoroacetate salt

β-Defensin 2 human recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

Sigma-Aldrich

D9690

β-Defensin 2 human

β-Defensin 1 human ≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

Sigma-Aldrich

D9565

β-Defensin 1 human

Cefpirome sulfate

Sigma-Aldrich

A3862

Cefpirome sulfate

description

≥95% (HPLC)

description

recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

description

≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

description

-

mode of action

cell membrane | interferes

mode of action

cell wall synthesis | interferes

mode of action

cell wall synthesis | interferes

mode of action

cell wall synthesis | interferes

antibiotic activity spectrum

Gram-positive bacteria, Gram-negative bacteria, viruses

antibiotic activity spectrum

Gram-positive bacteria, viruses, fungi, Gram-negative bacteria

antibiotic activity spectrum

Gram-positive bacteria, fungi, viruses, Gram-negative bacteria

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥95% (HPLC)

assay

-

assay

≥98% (HPLC and SDS-PAGE)

assay

-

form

powder (Lyophilisate)

form

lyophilized powder (from 10 mM acetic acid)

form

lyophilized powder (from 10 mM acetic acid)

form

powder

solubility

H2O: 1 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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