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Key Documents

D0406200

Deptropine citrate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dibenzheptropine citrate salt

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About This Item

Empirical Formula (Hill Notation):
C23H27NO · C6H8O7
CAS Number:
Molecular Weight:
525.59
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

deptropine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C23H27NO.C6H8O7/c1-24-18-12-13-19(24)15-20(14-18)25-23-21-8-4-2-6-16(21)10-11-17-7-3-5-9-22(17)23;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-9,18-20,23H,10-15H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

CHQGYMXXKZPWOI-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Deptropine citrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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[Alarming increase in deptropine poisonings].
S M Dreijer-van der Glas
Nederlands tijdschrift voor geneeskunde, 140(11), 628-629 (1996-03-16)
[Alarming increase in deptropine poisonings].
R W Griffioen
Nederlands tijdschrift voor geneeskunde, 140(11), 629-630 (1996-03-16)
DIBENZHEPTROPINE CITRATE ("BRONTINA")--A DOUBLE BLIND TRIAL IN CHRONIC CHEST DISEASE.
M W MCNICOL et al.
British journal of diseases of the chest, 58, 135-140 (1964-07-01)
B H Stricker et al.
Nederlands tijdschrift voor geneeskunde, 136(28), 1362-1365 (1992-07-11)
Since 1986 the Netherlands Centre for Monitoring of Adverse Reactions to Drugs has received 16 reports concerning psychic effects attributed to the use of deptropine citrate (Brontine) in children ranging from one to ten years of age. Within 1 to
Uptake of quaternary ammonium compounds into rat intestinal brush border membrane vesicles.
P G Ruifrok
Biochemical pharmacology, 30(19), 2637-2641 (1981-10-01)

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